Skin inflammation is an evolutionary-honed protective mechanism that serves to clear
noxious cues and irritants and initiate regeneration. Calcium-permeable transient-receptor …

Transient receptor potential vanilloid 4 (TRPV4) channel responds to temperature, as well
as various mechanical and chemical stimuli. This non-selective cation channel is expressed …

Somatosensation allows us to perceive sensory stimuli at the surface of and inside the body.
One sensation, itch, plays a protective role under acute conditions to alert us to potentially …

Among the various aspects of the present disclosure is the provision of compositions and
methods for treating hair regeneration disorders or conditions such as hair loss or thinning …

ةيتاوللا راص تنا، ةيديزيلا كلام، ةقدوب رامع abstract: Transient receptor potential vanilloid 4
(TRPV4) channel responds to temperature, as well as various mechanical and chemical …

Whilst acute itch is a beneficial sensation that serves to remove irritants and potentially
harmful agents from the skin by eliciting a scratch reflex, chronic itch is a debilitating …

Background: Recurrent and intractable chronic itch is a world-wide problem but
mechanisms, especially the neural mechanisms, underlying chronic itch still remain unclear …

Psoriasis is a common inflammatory skin disease. 70-80% of patients with psoriasis also
suffer from histamine-independent pruritus. Itch signals are transmitted by dorsal root …

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