[HTML][HTML] Nanoemulsions for drug delivery

RJ Wilson, Y Li, G Yang, CX Zhao - Particuology, 2022 - Elsevier
Emulsions are liquid–liquid dispersions with one liquid phase dispersed in the other liquid
phase as small droplets. Nanoemulsions are nano-sized emulsions with sizes ranging from …

The role of functional excipients in solid oral dosage forms to overcome poor drug dissolution and bioavailability

J Van der Merwe, J Steenekamp, D Steyn, J Hamman - Pharmaceutics, 2020 - mdpi.com
Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution
rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The …

Recent advances in improving the bioavailability of hydrophobic/lipophilic drugs and their delivery via self-emulsifying formulations

RK Ameta, K Soni, A Bhattarai - Colloids and Interfaces, 2023 - mdpi.com
Formulations based on emulsions for enhancing hydrophobic and lipophilic drug delivery
and its bioavailability have attracted a lot of interest. As potential therapeutic agents, they are …

Comparing microfluidics and ultrasonication as formulation methods for developing hempseed oil nanoemulsions for oral delivery applications

F Fathordoobady, N Sannikova, Y Guo, A Singh… - Scientific Reports, 2021 - nature.com
Emerging formulation technologies aimed to produce nanoemulsions with improved
characteristics, such as stability are attractive endeavors; however, comparisons between …

Self-nanoemulsifying drug delivery system of fisetin: Formulation, optimization, characterization and cytotoxicity assessment

R Kumar, R Khursheed, R Kumar, A Awasthi… - Journal of drug delivery …, 2019 - Elsevier
Fisetin is a plant derived flavonoid that possesses anti-cancer, anti-oxidant and anti-
Parkinson's activities. However, due to its lipophilicity it suffers from dissolution rate limited …

Enhanced antioxidant and anti-inflammatory effects of self-nano and microemulsifying drug delivery systems containing curcumin

L Józsa, G Vasvári, D Sinka, D Nemes, Z Ujhelyi… - Molecules, 2022 - mdpi.com
Turmeric has been used for decades for its antioxidant and anti-inflammatory effect, which is
due to an active ingredient isolated from the plant, called curcumin. However, the extremely …

Self microemulsifying drug delivery system of lurasidone hydrochloride for enhanced oral bioavailability by lymphatic targeting: in vitro, Caco-2 cell line and in vivo …

MH Patel, KK Sawant - European Journal of Pharmaceutical Sciences, 2019 - Elsevier
The global aim of this research was to develop and evaluate self-microemulsifying drug
delivery system (SMEDDS) to improve oral bioavailability of Lurasidone Hydrochloride (LH) …

[HTML][HTML] Design and characterization of propolis extract loaded self-nano emulsifying drug delivery system as immunostimulant

A Fitria, S Hanifah, L Chabib, AM Uno… - Saudi Pharmaceutical …, 2021 - Elsevier
This current study aims to optimize, characterize, and observe the stability of the self-nano
emulsifying drug delivery system (SNEDDS) of propolis extract (PE) for improving the …

Impact of solidification on micromeritic properties and dissolution rate of self-nanoemulsifying delivery system loaded with docosahexaenoic acid

D Ghosh, SK Singh, R Khursheed… - Drug development …, 2020 - Taylor & Francis
Abstract Development of self-nanoemulsifying drug delivery systems (SNEDDS) of
docosahexaenoic acid (DHA) is reported with the aim to achieve enhanced dissolution rate …

Methotrexate-loaded metal-organic frameworks on the basis of γ-cyclodextrin: Design, characterization, in vitro and in vivo investigation

I Kritskiy, T Volkova, T Sapozhnikova, A Mazur… - Materials Science and …, 2020 - Elsevier
In this work, metal-organic frameworks on the basis of γ-cyclodextrin (γCD-MOF) were
proposed as carriers for methotrexate (MTX) which is widely used as chemotherapy agent …