Cancer gene analysis of liquid‐based cytology specimens using next‐generation sequencing: a technical report of bimodal DNA‐and RNA‐based panel application
T Akahane, T Isochi‐Yamaguchi… - Diagnostic …, 2023 - Wiley Online Library
Background As liquid‐based cytology (LBC) specimens harbor high‐quality DNA, genomic
analysis using LBC specimens is beneficial for integrative diagnosis. This study aimed to …
analysis using LBC specimens is beneficial for integrative diagnosis. This study aimed to …
[HTML][HTML] Clinicopathological and genetic characteristics of patients of different ages with diffuse sclerosing variant papillary thyroid carcinoma
Simple Summary Diffuse sclerosing variant papillary thyroid carcinoma is a rare variant of
papillary thyroid carcinoma that is most frequently observed in young patients with different …
papillary thyroid carcinoma that is most frequently observed in young patients with different …
[HTML][HTML] Expression of pY397-FAK and Its miR Regulators Drive Dedifferentiation in the Thyroid Neoplasia Spectrum
V Ignjatović Jocić, J Janković Miljuš, T Išić Denčić… - Cells, 2023 - mdpi.com
Thyroid carcinomas are growing malignancies worldwide. They encompass several
diagnostic categories with varying degrees of dedifferentiation. Focal adhesion kinase is …
diagnostic categories with varying degrees of dedifferentiation. Focal adhesion kinase is …
Drug-induced inhibition of HMGA and EZH2 activity as a possible therapy for anaplastic thyroid carcinoma
M De Martino, S Pellecchia, M Decaussin-Petrucci… - Cell Cycle, 2023 - Taylor & Francis
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive and lethal neoplasms in
humans, and just limited progresses have been made to extend patient survival and …
humans, and just limited progresses have been made to extend patient survival and …
[HTML][HTML] Long-term survival outcomes of systemic therapy in patients with isolated and mixed medullary thyroid cancer
Background Medullary thyroid carcinoma (MTC) is an uncommon thyroid cancer with limited
treatment options for advanced disease. A small subset exhibits mixed MTC histology with …
treatment options for advanced disease. A small subset exhibits mixed MTC histology with …
[HTML][HTML] Cancer Predisposition Syndromes and Thyroid Cancer: Keys for a Short Two-Way Street
I Balinisteanu, MC Panzaru, L Caba, MC Ungureanu… - Biomedicines, 2023 - mdpi.com
Cancer predisposition syndromes are entities determined especially by germinal pathogenic
variants, with most of them autosomal dominantly inherited. The risk of a form of cancer is …
variants, with most of them autosomal dominantly inherited. The risk of a form of cancer is …
Epidermal growth factor receptor activation confers resistance to lenvatinib in thyroid cancer cells
K Ohno, T Shibata, K Ito - Cancer Science, 2022 - Wiley Online Library
Thyroid cancer is the most common endocrine malignancy. A multitargeted tyrosine kinase
inhibitor, lenvatinib, has been used for the treatment of advanced thyroid cancer. To …
inhibitor, lenvatinib, has been used for the treatment of advanced thyroid cancer. To …
[HTML][HTML] Medullary Thyroid Cancer: Molecular Drivers and Immune Cellular Milieu of the Tumour Microenvironment—Implications for Systemic Treatment
AJ Papachristos, H Serrao-Brown, AJ Gill… - Cancers, 2024 - mdpi.com
Simple Summary Medullary thyroid carcinoma (MTC) is driven by a small number of
pathogenic genetic variants and tumours usually exhibit a correspondingly low tumour …
pathogenic genetic variants and tumours usually exhibit a correspondingly low tumour …
[HTML][HTML] The Incidence Trend and Management of Thyroid Cancer—What Has Changed in the Past Years: Own Experience and Literature Review
K Kaliszewski, D Diakowska, M Miciak, K Jurkiewicz… - Cancers, 2023 - mdpi.com
Simple Summary The incidence of thyroid cancer (TC) has increased greatly since the
1970s, mostly because of higher detection of the small forms of papillary thyroid cancer …
1970s, mostly because of higher detection of the small forms of papillary thyroid cancer …
Advances in pharmacotherapy for advanced thyroid cancer of follicular origin (PTC, FTC). New approved drugs and future therapies
G Elia, SM Ferrari, F Ragusa, SR Paparo… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The most common altered signaling found in aggressive iodine-refractory
thyroid cancers derived from follicular cells (RAI-TC) are RTK, MAPK, PI3K, WNT, BRAF …
thyroid cancers derived from follicular cells (RAI-TC) are RTK, MAPK, PI3K, WNT, BRAF …