Simultaneous stabilization and functionalization of gold nanoparticles via biomolecule conjugation: Progress and perspectives

JW Lee, SR Choi, JH Heo - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Gold nanoparticles (AuNPs) are used in various biological applications because of their
small surface area-to-volume ratios, ease of synthesis and modification, low toxicity, and …

The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review

Y Cao, Y Gong, L Liu, Y Zhou, X Fang… - Journal of Applied …, 2017 - Wiley Online Library
With the rapid development of nanotechnologies, nanoparticles (NPs) are increasingly
produced and used in many commercial products, which could lead to the contact of human …

Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach

YH Cheng, C He, JE Riviere, NA Monteiro-Riviere… - ACS …, 2020 - ACS Publications
Numerous studies have engineered nanoparticles with different physicochemical properties
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …

Protein-gold nanoparticle interactions and their possible impact on biomedical applications

J Liu, Q Peng - Acta biomaterialia, 2017 - Elsevier
In the past few years, concerns of protein-gold nanoparticles (AuNP) interaction have been
continuously growing in numerous potential biomedical applications. Despite the advances …

Interaction of gold nanoparticles with proteins and cells

P Wang, X Wang, L Wang, X Hou, W Liu… - … and technology of …, 2015 - iopscience.iop.org
Abstract Gold nanoparticles (Au NPs) possess many advantages such as facile synthesis,
controllable size and shape, good biocompatibility, and unique optical properties. Au NPs …

Techniques for the experimental investigation of the protein corona

C Carrillo-Carrion, M Carril, WJ Parak - Current Opinion in Biotechnology, 2017 - Elsevier
Highlights•Direct versus indirect analysis of the protein corona.•In situ measurements of
protein corona versus measurements requiring purification.•Characterization apart from …

Size, shape and surface chemistry of nano-gold dictate its cellular interactions, uptake and toxicity

C Carnovale, G Bryant, R Shukla, V Bansal - Progress in Materials Science, 2016 - Elsevier
Colloidal gold is undoubtedly one of the most extensively studied nanomaterials, with 1000s
of different protocols currently available to synthesise gold nanoparticles (AuNPs). While …

Dark-field/hyperspectral microscopy for detecting nanoscale particles in environmental nanotoxicology research

R Fakhrullin, L Nigamatzyanova… - Science of The Total …, 2021 - Elsevier
Nanoscale contaminants (including engineered nanoparticles and nanoplastics) pose a
significant threat to organisms and environment. Rapid and non-destructive detection and …

Gold nanoparticle should understand protein corona for being a clinical nanomaterial

F Charbgoo, M Nejabat, K Abnous, F Soltani… - Journal of controlled …, 2018 - Elsevier
Gold nanoparticles (AuNPs) have attracted great attention in biomedical fields due to their
unique properties. However, there are few reports on clinical trial of these nanoparticles. In …

Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities

JLS Au, BZ Yeung, MG Wientjes, Z Lu… - Advanced drug delivery …, 2016 - Elsevier
Advances in molecular medicine have led to identification of worthy cellular and molecular
targets located in extracellular and intracellular compartments. Effectiveness of cancer …