[HTML][HTML] Progress in 7SK ribonucleoprotein structural biology

MB Camara, AM Sobeh, CD Eichhorn - Frontiers in Molecular …, 2023 - frontiersin.org
The 7SK ribonucleoprotein (RNP) is a dynamic and multifunctional regulator of RNA
Polymerase II (RNAPII) transcription in metazoa. Comprised of the noncoding 7SK RNA …

Computer-aided comprehensive explorations of RNA structural polymorphism through complementary simulation methods

K Röder, G Stirnemann, P Faccioli, S Pasquali - QRB discovery, 2022 - cambridge.org
While RNA folding was originally seen as a simple problem to solve, it has been shown that
the promiscuous interactions of the nucleobases result in structural polymorphism, with …

Characterization of SLA RNA promoter from dengue virus and its interaction with the viral non-structural NS5 protein

K Brillet, M Janczuk-Richter, A Poon, J Laukart-Bradley… - Biochimie, 2024 - Elsevier
The Dengue virus (DENV) is the most significant arthropod-borne viral pathogen in humans
with 400 million infections annually. DENV comprises four distinct serotypes (DENV-1 to− 4) …

[HTML][HTML] A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA

VV Pham, M Gao, JL Meagher, JL Smith… - Communications …, 2022 - nature.com
Productive transcriptional elongation of many cellular and viral mRNAs requires
transcriptional factors to extract pTEFb from the 7SK snRNP by modulating the association …

Alternate structures regulate transcription and translation of RNA viral genomes

VV Pham - 2022 - search.proquest.com
With the emergence of new RNA-structure related techniques, it is becoming increasingly
clear that viral RNA genomes are structurally and functionally plastic, which drive multiple …