[HTML][HTML] Microbiome as a biomarker and therapeutic target in pancreatic cancer

G Pourali, D Kazemi, AS Chadeganipour… - BMC microbiology, 2024 - Springer
Studying the effects of the microbiome on the development of different types of cancer has
recently received increasing research attention. In this context, the microbial content of …

[HTML][HTML] Decoding the microbiota metabolome in hepatobiliary and pancreatic cancers: Pathways to precision diagnostics and targeted therapeutics

Y Xu, J Le, J Qin, Y Zhang, J Yang, Z Chen, C Li… - Pharmacological …, 2024 - Elsevier
We delve into the critical role of the gut microbiota and its metabolites in the pathogenesis
and progression of hepatobiliary and pancreatic (HBP) cancers, illuminating an urgent need …

[HTML][HTML] Bile Microbiome Signatures Associated with Pancreatic Ductal Adenocarcinoma Compared to Benign Disease: A UK Pilot Study

N Merali, T Chouari, J Terroire, MD Jessel… - International journal of …, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) has a very poor survival. The intra-tumoural
microbiome can influence pancreatic tumourigenesis and chemoresistance and, therefore …

[HTML][HTML] Effect of sphincter of Oddi dysfunction on the abundance of biliary microbiota (biliary microecology) in patients with common bile duct stones

L Liu, Z Zhao, X Hou, J Wu - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Objective Biliary calculi, a common benign disease of the gastrointestinal tract, are affected
by multiple factors, including diet, lifestyle, living environment, and personal and genetic …

[HTML][HTML] Uncovering Microbial Composition of the Tissue Microenvironment in Bladder Cancer using RNA Sequencing Data

R Yao, B Ai, Z Wang, B Shen, G Xue, D Yu - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
Purpose: Bladder cancer (BC) is one of the top 10 common tumors in the world. It has been
reported that microbiota can colonize tissues and play important roles in tumorigenesis and …

Escherichia coli‐Induced cGLIS3‐Mediated Stress Granules Activate the NF‐κB Pathway to Promote Intrahepatic Cholangiocarcinoma Progression

FP Kang, ZW Chen, CY Liao, YD Wu, G Li… - Advanced …, 2024 - Wiley Online Library
Patients with concurrent intrahepatic cholangiocarcinoma (ICC) and hepatolithiasis
generally have poor prognoses. Hepatolithiasis is once considered the primary cause of …

[HTML][HTML] Interplay between the Human Microbiome and Biliary Tract Cancer: Implications for Pathogenesis and Therapy

C Ye, C Dong, Y Lin, H Shi, W Zhou - Microorganisms, 2023 - mdpi.com
Biliary tract cancer, encompassing intrahepatic and extrahepatic cholangiocarcinoma as
well as gallbladder carcinoma, stands as a prevalent malignancy characterized by …

Getting off tract: contributions of intraorgan microbiota to cancer in extraintestinal organs

SC Thomas, G Miller, X Li, D Saxena - Gut, 2024 - gut.bmj.com
The gastrointestinal ecosystem has received the most attention when examining the
contributions of the human microbiome to health and disease. This concentration of effort is …

The microbial composition of pancreatic ductal adenocarcinoma: A systematic review of 16S rRNA gene sequencing

N Merali, T Chouari, C Sweeney… - … Journal of Surgery, 2024 - journals.lww.com
Background: Pancreatic cancer, specifically pancreatic ductal adenocarcinoma (PDAC),
continues to pose a significant clinical and scientific challenge. The most significant finding …

肿瘤内微生物组的研究进展

李欣然, 梁依依, 屠红 - 中国癌症杂志, 2023 - china-oncology.com
肿瘤内微生物组是指存在于肿瘤中并构成肿瘤微环境的微生物群体. 虽然肿瘤病毒的研究已有百
余年历史, 但细菌, 真菌等其他微生物在肿瘤中的存在现象及生物学意义却一直未有定论 …