Nonalcoholic fatty liver disease (NAFLD) has become the dominant form of chronic liver
disease in children and adolescents with the increasing prevalence of obesity worldwide …

The conventional paradigm of nonalcoholic fatty liver disease representing the “hepatic
manifestation of the metabolic syndrome” is outdated. We identified and summarized …

Although discussion of the obesity epidemic had become a cocktail party cliché, its impact
on public health cannot be dismissed. In the past decade, cancer had joined the list of …

Vitamin D through its active form 1a-25-dihydroxyvtamin D [1, 25 (OH) 2 D] is a secosteroid
hormone that plays a key role in mineral metabolism. Recent years have witnessed a …

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to
one-third of the adult population in industrialised countries. NAFLD incorporates …

Genome‐wide association studies (GWAS) have identified several risk loci for nonalcoholic
fatty liver disease (NAFLD). Previous studies have largely relied on small sample sizes and …

Background & aims Non-alcoholic fatty liver disease (NAFLD), with its increasing prevalence
and association with various co-morbidities, such as diabetes, cardiovascular disease and …

Sterol regulatory element-binding proteins (SREBPs) are transcription factors that control
lipid homeostasis. SREBP activation is regulated by a negative feedback loop in which …

The role of vitamin D in curtailing the development of obesity and comorbidities such as the
metabolic syndrome (MetS) and type 2 diabetes has received much attention recently …

Background The liver plays a central role in the maintenance of homeostasis and health in
general. However, there is substantial inter-individual variation in hepatic gene expression …