Systematic review of the alkaloid constituents in several important medicinal plants of the Genus Corydalis

AP Deng, Y Zhang, L Zhou, CZ Kang, CG Lv, LP Kang… - Phytochemistry, 2021 - Elsevier
The genus Corydalis is a botanical source of various pharmaceutically active components.
Its member species have been widely used in traditional medicine systems in Southeast …

Calycosin reduces myocardial fibrosis and improves cardiac function in post-myocardial infarction mice by suppressing TGFBR1 signaling pathways

G Chen, H Xu, T Xu, W Ding, G Zhang, Y Hua, Y Wu… - Phytomedicine, 2022 - Elsevier
Background Excessive myocardial fibrosis is the pathological basis of heart failure following
myocardial infarction (MI). Although calycosin improves cardiac function, its effect on cardiac …

microRNA-193-3p attenuates myocardial injury of mice with sepsis via STAT3/HMGB1 axis

J Pan, B Alexan, D Dennis, C Bettina… - Journal of translational …, 2021 - Springer
Objective Little is known regarding the functional role of microRNA-193-3p (miR-193-3p) in
sepsis. Hence, the aim of the present study was to investigate the effect of miR-193-3p on …

[HTML][HTML] Targeting the JAK2/STAT3 signaling pathway with natural plants and phytochemical ingredients: A novel therapeutic method for combatting cardiovascular …

B Guo, Y Yu, M Wang, R Li, X He, S Tang, Q Liu… - Biomedicine & …, 2024 - Elsevier
The aim of this article is to introduce the roles and mechanisms of the JAK2/STAT3 pathway
in various cardiovascular diseases, such as myocardial fibrosis, cardiac hypertrophy …

Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity

JH Han, JH Ju, YS Lee, JH Park, IJ Yeo, MH Park… - Scientific reports, 2018 - nature.com
Astaxanthin (AXT) is classified as a xanthophyll carotenoid compound which have broader
functions including potent antioxidant, anti-inflammatory and neuroprotective properties …

Isolation, synthesis and bioactivity evaluation of isoquinoline alkaloids from Corydalis hendersonii Hemsl. against gastric cancer in vitro and in vivo

T Luo, Z Li, XM Deng, K Jiang, D Liu, HH Zhang… - Bioorganic & Medicinal …, 2022 - Elsevier
Isoquinoline alkaloid displays significant anti-gastric cancer effects due to its unique
structure, which is attracting more and more attention for the development of anti-gastric …

Bioactive Sesquiterpenoids from the Peeled Stems of Syringa pinnatifolia

R Zhang, X Feng, G Su, Z Mu, H Zhang… - Journal of natural …, 2018 - ACS Publications
Fourteen new sesquiterpenoids, alashanoids A–H (1, 2, and 4–9),(+)-2, 9-humuladien-6-ol-
8-one (3b), and five pairs of enantiomers (1 and 4–7), along with eight known analogues (3a …

Determination of selected isoquinoline alkaloids from Mahonia aquifolia; Meconopsis cambrica; Corydalis lutea; Dicentra spectabilis; Fumaria officinalis; Macleaya …

A Petruczynik, T Plech, T Tuzimski, J Misiurek… - Toxins, 2019 - mdpi.com
Alkaloids have protective functions for plants and can play an important role in living
organisms. Alkaloids may have a wide range of pharmacological activities. Many of them …

The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 …

F Ge, X Gao, X Zhou, J Li, X Ma, M Huang, S Wuken… - Chinese Medicine, 2023 - Springer
Background There is a characteristic Tibetan folk medicine in China named Corydalis
hendersonii Hemsl.(CH) has been used for treatment of cardiovascular related diseases …

Ilex asprella aqueous extracts exert in vivo anti-inflammatory effects by regulating the NF-κB, JAK2/STAT3, and MAPK signaling pathways

X Yang, X Gao, B Du, F Zhao, X Feng, H Zhang… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance Ilex asprella (Hook. et Arn.) Champ. ex Benth.(IA)
is a representative medicinal plant from the South of the Five Ridges of China. Its roots (RIA) …