Simple Summary Interferons are cytokines that play key roles in the activation of cellular
components of the immune response, such as dendritic cells, macrophages and T cells …

Interferons (IFNs) are a large family of pleiotropic cytokines that regulate both innate and
adaptive immunity and show anti-cancer effects in various cancer types. Moreover, it was …

Introduction DNA vaccines containing a fusion of the gene encoding chemokine MIP-3α
(CCL20), the ligand for CCR6 on immature dendritic cells (DCs), to melanoma-associated …

Since the turn of the century, advances in targeted therapy and immunotherapy have
revolutionized the treatment of cancer. Although these approaches have far outperformed …

The clinical significance and comprehensive features of chemokines and their receptors in
lung adenocarcinoma (LUAD) have not been clarified. We aimed to characterize the …

The tumor microenvironment (TME) is crucial to neoplastic processes, fostering proliferation,
angiogenesis and metastasis. Epigenetic regulations, primarily including DNA and RNA …

Decitabine's early successful therapeutic outcomes in hematologic malignancies have led to
regulatory approvals from the Food and Drug Administration (FDA) and the European …

Background Previous studies have demonstrated enhanced efficacy of vaccine formulations
that incorporate the chemokine macrophage inflammatory protein 3α (MIP-3α) to direct …

Chemotherapy is the main treatment for acute myeloid leukemia (AML), but the therapeutic
efficacy is modest, and most commonly manifests as relapse from remission. Thus …

Lengthy tuberculosis (TB) treatment is required to overcome the ability of a subpopulation of
persistent Mycobacterium tuberculosis (Mtb) to remain in a non-replicating, antibiotic …