Transmembrane transport of small organic and inorganic molecules is one of the
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …

The lack of effective treatments for neurodegenerative diseases (NDs) is an important
current concern. Lipid nanoparticles can deliver innovative combinations of active molecules …

Nose-to-brain delivery presents a promising alternative route compared to classical blood–
brain barrier passage, especially for the delivery of high molecular weight drugs. In general …

The administration of liposomes via nose-to-brain delivery is expected to become a strategy
for efficient drug delivery to the central nervous system. Efficient nose-to-brain delivery and …

In the past decade, RNA therapeutics have gone from being a promising concept to one of
the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what …

Intranasal administration is a promising route for direct drug delivery to the brain; its
combination with nanocarriers enhances delivery. We have previously shown that intranasal …

Treatments for disease in the central nervous system (CNS) are limited because of
difficulties in agent penetration through the blood-brain barrier, achieving optimal dosing …

Background: Glutathione (GSH) is a tripeptide, which is recognised as a potent antioxidant
involving in numerous essential biological processes, and has been used for interventions …

Epilepsy is a chronic neurological disorder affecting 70 million people globally. One of the
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …

Research on the neuroprotective effect of pituitary adenylate cyclase-activating polypeptide
(PACAP) and its use as a therapeutic agent has grown over the past 30 years. Both in vitro …