The process of sprouting angiogenesis involves activating endothelial cells (ECs) in a
quiescent monolayer of an existing vessel to degrade and migrate into the underlying matrix …

Introduction Fibrosis is a serious disease that occurs in many organs, such as kidney, liver
and lung. The deterioration of these organs ultimately leads to death. Due to the complex …

Cutaneous wound healing is a complex process, which is heavily dependent on successful
inflammatory action. Mitogen-activated protein kinase (MAPK)-activated protein kinase-2 …

Background: Colorectal cancer (CRC) is the most common malignant cancer worldwide.
Sanguisorba officinalis has been shown to have anti-inflammatory, anti-bacterial, antioxidant …

Phosphate, an essential nutrient, is available in organic and inorganic forms. The balance of
phosphate is central for cellular homeostasis through the genomic roles of DNA and RNA …

The intricacy of multiple feedback loops in the pathways downstream of Akt allows this
kinase to control multiple cellular processes in the cardiovascular system and precludes …

A number of pro‐fibrogenic stimuli, such as growth factors, cytokines, and extracellular
matrix (ECM) proteins, involve Akt and its downstream substrates in mediating their effects …

Akt1 belongs to the three‐gene Akt family and functions as a serine–threonine kinase
regulating phosphorylation of an array of substrates and mediating cellular processes such …

Cytokines and growth factors are known to play an important role in the skin wound closure
process; however, in knockout organisms, the levels of these molecules can undergo …

Background: Activation of Akt and increased expression of integrin β 3 are the two most
important changes that have been linked to the attainment of metastatic potential by prostate …