[HTML][HTML] Base excision repair: mechanisms and impact in biology, disease, and medicine
Base excision repair (BER) corrects forms of oxidative, deamination, alkylation, and abasic
single-base damage that appear to have minimal effects on the helix. Since its discovery in …
single-base damage that appear to have minimal effects on the helix. Since its discovery in …
Platelet Membrane Fragment Self‐Assembled Oral Hydrogel Microspheres for Restoring Intestinal Microvascular Injury
H Liu, Z Cai, F Wang, H Ruan, C Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Non‐invasive management of intestinal microvascular injury with hemorrhage under
constant biochemical‐mechanical encroachment of luminal contents is a major clinical …
constant biochemical‐mechanical encroachment of luminal contents is a major clinical …
[HTML][HTML] Administration of intestinal mesenchymal stromal cells reduces colitis-associated cancer in C57BL/6J mice modulating the immune response and gut …
L Hidalgo-García, AJ Ruiz-Malagon, F Huertas… - Pharmacological …, 2023 - Elsevier
Background Patients with inflammatory bowel disease (IBD) have a higher risk of
developing colitis-associated colorectal cancer (CAC) with poor prognosis. IBD etiology …
developing colitis-associated colorectal cancer (CAC) with poor prognosis. IBD etiology …
[HTML][HTML] Peptide fraction from sturgeon muscle by pepsin hydrolysis exerts anti-inflammatory effects in LPS-stimulated RAW264. 7 macrophages via MAPK and NF-κB …
R Gao, W Shu, Y Shen, Q Sun, W Jin, D Li, Y Li… - Food Science and …, 2021 - Elsevier
Previous studies have suggested that polypeptides extracted from milk, soybean, fish, eggs,
and meat possess potential anti-inflammatory effects. To date, few studies have reported the …
and meat possess potential anti-inflammatory effects. To date, few studies have reported the …
[HTML][HTML] Proteins from the DNA damage response: Regulation, dysfunction, and anticancer strategies
C Molinaro, A Martoriati, K Cailliau - Cancers, 2021 - mdpi.com
Simple Summary Cells respond to genotoxic stress through complex protein pathways
called DNA damage response (DDR). These mechanisms ensure the preservation of …
called DNA damage response (DDR). These mechanisms ensure the preservation of …
[HTML][HTML] Inflammation and digestive cancer
H Waldum, R Fossmark - International Journal of Molecular Sciences, 2023 - mdpi.com
Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, ie, the
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …
Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 …
XL Zhao, L Yu, SD Zhang, K Ping, HY Ni, XY Qin… - International …, 2020 - Elsevier
Phenolic acids are found in natural plants, such as caffeic acid, rosmarinic acid, and
chlorogenic acid. They have long been used as pharmacological actives, owing to their anti …
chlorogenic acid. They have long been used as pharmacological actives, owing to their anti …
The role of chronic inflammation in various diseases and anti‐inflammatory therapies containing natural products
RX Wang, M Zhou, HL Ma, YB Qiao, QS Li - ChemMedChem, 2021 - Wiley Online Library
Chronic inflammation represents a long‐term reaction of the body's immune system to
noxious stimuli. Such a sustained inflammatory response sometimes results in lasting …
noxious stimuli. Such a sustained inflammatory response sometimes results in lasting …
Micronuclei, inflammation and auto-immune disease
M Kirsch-Volders, C Bolognesi, M Ceppi… - … Research/Reviews in …, 2020 - Elsevier
Auto-immune diseases (AUD) are characterized by an immune response to antigenic
components of the host itself. The etiology of AUD is not well understood. The available …
components of the host itself. The etiology of AUD is not well understood. The available …
[HTML][HTML] Epigenetic modulation of inflammatory pathways in myometrial stem cells and risk of uterine fibroids
The period during which tissue and organ development occurs is particularly vulnerable to
the influence of environmental exposures. However, the specific mechanisms through which …
the influence of environmental exposures. However, the specific mechanisms through which …