[HTML][HTML] Base excision repair: mechanisms and impact in biology, disease, and medicine

D Gohil, AH Sarker, R Roy - International Journal of Molecular Sciences, 2023 - mdpi.com
Base excision repair (BER) corrects forms of oxidative, deamination, alkylation, and abasic
single-base damage that appear to have minimal effects on the helix. Since its discovery in …

Platelet Membrane Fragment Self‐Assembled Oral Hydrogel Microspheres for Restoring Intestinal Microvascular Injury

H Liu, Z Cai, F Wang, H Ruan, C Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Non‐invasive management of intestinal microvascular injury with hemorrhage under
constant biochemical‐mechanical encroachment of luminal contents is a major clinical …

[HTML][HTML] Administration of intestinal mesenchymal stromal cells reduces colitis-associated cancer in C57BL/6J mice modulating the immune response and gut …

L Hidalgo-García, AJ Ruiz-Malagon, F Huertas… - Pharmacological …, 2023 - Elsevier
Background Patients with inflammatory bowel disease (IBD) have a higher risk of
developing colitis-associated colorectal cancer (CAC) with poor prognosis. IBD etiology …

[HTML][HTML] Peptide fraction from sturgeon muscle by pepsin hydrolysis exerts anti-inflammatory effects in LPS-stimulated RAW264. 7 macrophages via MAPK and NF-κB …

R Gao, W Shu, Y Shen, Q Sun, W Jin, D Li, Y Li… - Food Science and …, 2021 - Elsevier
Previous studies have suggested that polypeptides extracted from milk, soybean, fish, eggs,
and meat possess potential anti-inflammatory effects. To date, few studies have reported the …

[HTML][HTML] Proteins from the DNA damage response: Regulation, dysfunction, and anticancer strategies

C Molinaro, A Martoriati, K Cailliau - Cancers, 2021 - mdpi.com
Simple Summary Cells respond to genotoxic stress through complex protein pathways
called DNA damage response (DDR). These mechanisms ensure the preservation of …

[HTML][HTML] Inflammation and digestive cancer

H Waldum, R Fossmark - International Journal of Molecular Sciences, 2023 - mdpi.com
Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, ie, the
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …

Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 …

XL Zhao, L Yu, SD Zhang, K Ping, HY Ni, XY Qin… - International …, 2020 - Elsevier
Phenolic acids are found in natural plants, such as caffeic acid, rosmarinic acid, and
chlorogenic acid. They have long been used as pharmacological actives, owing to their anti …

The role of chronic inflammation in various diseases and anti‐inflammatory therapies containing natural products

RX Wang, M Zhou, HL Ma, YB Qiao, QS Li - ChemMedChem, 2021 - Wiley Online Library
Chronic inflammation represents a long‐term reaction of the body's immune system to
noxious stimuli. Such a sustained inflammatory response sometimes results in lasting …

Micronuclei, inflammation and auto-immune disease

M Kirsch-Volders, C Bolognesi, M Ceppi… - … Research/Reviews in …, 2020 - Elsevier
Auto-immune diseases (AUD) are characterized by an immune response to antigenic
components of the host itself. The etiology of AUD is not well understood. The available …

[HTML][HTML] Epigenetic modulation of inflammatory pathways in myometrial stem cells and risk of uterine fibroids

Q Yang, M Ali, LS Treviño, A Mas, N Ismail… - International Journal of …, 2023 - mdpi.com
The period during which tissue and organ development occurs is particularly vulnerable to
the influence of environmental exposures. However, the specific mechanisms through which …