Oxidative stress with subsequent premutagenic oxidative DNA damage has been implicated
in colorectal carcinogenesis. The repair of oxidative DNA damage is initiated by lesion …

Simple Summary Cystic fibrosis (CF) is a genetic condition that affects the lungs, digestion,
and other body systems. People with CF have a higher chance of developing certain types …

Inflammation and disease are closely related. Inflammation can induce various diseases,
and diseases can promote inflammatory response, and two possibly induces each other in a …

The low-dose mixture hypothesis of carcinogenesis proposes that exposure to an
environmental chemical that is not individually oncogenic may nonetheless be capable of …

Background Systemic inflammatory markers are associated with patient survival in
pancreatic cancer (PC). The aim of this study was to investigate the prognostic significance …

Biological hypochlorous acid (HOCl), a reactive oxygen species (ROS) with high activity,
plays a crucial role in normal biochemical functions and abnormal pathological processes …

Gastroesophageal reflux disease (GERD) leads to the accumulation of bile-induced reactive
oxygen species and oxidative stress in esophageal tissues, causing inflammation and DNA …

The notion that neutrophils only perform a specific set of single functions in the body has
changed with the advancement of research methods. As the most abundant myeloid cells in …

Triazolopyridines are an important kind of fused-ring compounds. A HOCl-promoted
triazolopyridine formation strategy is reported here for the first time in which hypochlorous …

The therapeutic suppression of oxidative stress represents an attractive therapeutic target
across an array of inflammatory disease setting. The nuclear factor erythroid 2-related factor …