Background. Gastrointestinal (GI) cancers are one of the most relevant causes of death
globally, frequently associated with poor dietary patterns. The Mediterranean Diet (MedDiet) …

Conspectus DNA repair enzymes continuously provide surveillance throughout our cells,
protecting the enclosed DNA from the damage that is constantly arising from oxidation …

This study emphasizes the importance of considering the metabolic and toxicity mechanisms
of environmental concern chemicals in real-life exposure scenarios. Furthermore …

Oxidative and alkylating DNA damage occurs under normal physiological conditions and
exogenous exposure to DNA damaging agents. To counteract DNA base damage, cells …

Introduction Typhoid toxin-expressing Salmonella enterica causes DNA damage in the
intestinal mucosa in vivo, activating the DNA damage response (DDR) in the absence of …

The synergistic relationships between Cancer, Aging, and Infection, here referred to as the
CAIn Triangle, are significant determinants in numerous health maladies and mortality rates …

Clonal hematopoiesis (CH) occurs in hematopoietic stem cells with increased risks of
progressing to hematologic malignancies. CH mutations are predominantly found in aged …

Bacterial genotoxins cause DNA damage in eukaryotic cells, resulting in activation of the
DNA damage response (DDR) in vitro. These toxins are produced by Gram-negative …

Highlights aPLs are involved in the induction of a pro-oxidative state in APS patients
Oxidative stress is a potential biomarker of thrombosis risk in APS patients Oxidative stress …

Background Evidence of the association between particles with a diameter of 2.5 μm or less
(PM 2.5) in long term and ovarian cancer (OC) mortality is limited. Methods This prospective …