Targeting xanthine oxidase by natural products as a therapeutic approach for mental disorders

M Martorell, X Lucas, P Alarcón-Zapata… - Current …, 2021 - ingentaconnect.com
Mental disorders comprise diverse human pathologies, including depression, bipolar
affective disorder, schizophrenia, and dementia that affect millions of people around the …

MicroRNAs as the critical regulators of tumor angiogenesis in liver cancer

A Fanoodi, A Maharati, I Akhlaghipour… - … -Research and Practice, 2023 - Elsevier
Liver cancer is one of the most common malignancies in human digestive system. Despite
the recent therapeutic methods, there is a high rate of mortality among liver cancer patients …

The preoperative neutrophil lymphocyte ratio and platelet lymphocyte ratio predicts disease-free survival in resectable esophageal squamous cell carcinoma

Z Zheng, C Yang, C Cai, H Zhu - Cancer Management and …, 2021 - Taylor & Francis
Background Recent studies have revealed that the presence of systemic inflammation is
associated with poor survival for esophageal squamous cell carcinoma. We aimed to …

Understanding the impact of obesity on ageing in the radiance of DNA metabolism

SG Chowdhury, S Misra, P Karmakar - The journal of nutrition, health & …, 2023 - Springer
Ageing is a multi-factorial phenomenon which is considered as a major risk factor for the
development of neurodegeneration, osteoporosis, cardiovascular disease, dementia …

Niosomal formulation of mefenamic acid for enhanced cancer targeting; preparation, characterization and biodistribution study using radiolabeling technique

MA Shewaiter, AA Selim, HM Rashed… - Journal of Cancer …, 2023 - Springer
Background This work aimed to prepare niosomal formulations of an anticancer agent
[mefenamic acid (MEF)] to enhance its cancer targeting. 131I was utilized as a radiolabeling …

Defective DNA polymerase beta invoke a cytosolic DNA mediated inflammatory response

S Zhao, JA Goewey Ruiz, M Sebastian… - Frontiers in …, 2022 - frontiersin.org
Base excision repair (BER) has evolved to maintain the genomic integrity of DNA following
endogenous and exogenous agent induced DNA base damage. In contrast, aberrant BER …

Fasting hyperglycaemia and fatty liver drive colorectal cancer: a retrospective analysis in 1145 patients

L Crudele, C De Matteis, F Novielli, S Petruzzelli… - Internal and Emergency …, 2024 - Springer
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) represents
the hepatic manifestation of increased adiposopathy, whose pathogenetic features have …

Anti-Inflammatory Activity and Mechanism of Cryptochlorogenic Acid from Ageratina adenophora

X Ma, SK Okyere, L Hu, J Wen, Z Ren, J Deng, Y Hu - Nutrients, 2022 - mdpi.com
Ageratina adenophora is an invasive plant known for its toxicity to livestock. Current
research on this plant has shifted from toxicity prevention to the beneficial utilization of plant …

[HTML][HTML] Early occupational exposure to lead on neutrophil-to-lymphocyte ratio and genotoxicity

Y Meng, K Wang, T Wang, Y Tu, S Gong, Y Zhang… - Environment …, 2021 - Elsevier
Abstract Background Lead (Pb) is known to induce detrimental health effects in exposed
populations, including hematotoxicity and genotoxicity. Complete blood count (CBC) is a …

MiR-325-3p mediate the CXCL17/CXCR8 axis to regulate angiogenesis in hepatocellular carcinoma

L Li, Y Ji, YC Chen, ZJ Zhen - Cytokine, 2021 - Elsevier
Abstract Introduction MicroRNA-325-3p (miR-325-3p) is involved in the progression of a
great number of tumors. However, the regulatory mechanism of miR-325-3p on …