[HTML][HTML] Impact of natural compounds on neurodegenerative disorders: from preclinical to pharmacotherapeutics

M Sharifi-Rad, C Lankatillake, DA Dias… - Journal of Clinical …, 2020 - mdpi.com
Among the major neurodegenerative disorders (NDDs), Alzheimer's disease (AD) and
Parkinson's disease (PD), are a huge socioeconomic burden. Over many centuries, people …

[HTML][HTML] Extraction of high-value chemicals from plants for technical and medical applications

P Kapadia, AS Newell, J Cunningham… - International journal of …, 2022 - mdpi.com
Plants produce a variety of high-value chemicals (eg, secondary metabolites) which have a
plethora of biological activities, which may be utilised in many facets of industry (eg …

[HTML][HTML] Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain

A Khan, T Ali, SU Rehman, MS Khan, SI Alam… - Frontiers in …, 2018 - frontiersin.org
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …

[HTML][HTML] Natural compounds for Alzheimer's disease therapy: a systematic review of preclinical and clinical studies

S Andrade, MJ Ramalho, JA Loureiro… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …

Polymeric nanoparticles for nasal drug delivery to the brain: relevance to Alzheimer's disease

N Rabiee, S Ahmadi, R Afshari, S Khalaji… - Advanced …, 2021 - Wiley Online Library
Currently, Alzheimer's disease (AD) accounts for more than half of all dementia cases.
Although genetics, age, and environmental factors affect the disease, the cause of AD is not …

Traditional Chinese medicine for Alzheimer's disease and other cognitive impairment: a review

H Pei, L Ma, Y Cao, F Wang, Z Li, N Liu… - The American journal …, 2020 - World Scientific
Cognitive impairment (CI) refers to the dysfunction of memory, language, visual space,
execution, calculation, understanding, and judgment in one or more aspects. With global …

[HTML][HTML] Ginsenoside Rk3 ameliorates Aβ-induced neurotoxicity in APP/PS1 model mice via AMPK signaling pathway

L She, L Xiong, L Li, J Zhang, J Sun, H Wu… - Biomedicine & …, 2023 - Elsevier
Alzheimer's disease (AD) has become a major public health problem affecting the elderly
population, and there is currently no effective treatment. Although the pathogenesis of AD is …

[HTML][HTML] Investigation of the neuroprotective effects of crocin via antioxidant activities in HT22 cells and in mice with Alzheimer's disease

C Wang, X Cai, W Hu, Z Li, F Kong… - International …, 2019 - spandidos-publications.com
Due to its complex pathogenesis, the prevention and therapization of Alzheimer's disease
(AD) remains a serious challenge. Crocin, the main compound isolated from Crocus sativus …

[HTML][HTML] Natural therapeutics in aid of treating alzheimer's disease: a green gateway toward ending quest for treating neurological disorders

BA Bhat, A Almilaibary, RA Mir, BM Aljarallah… - Frontiers in …, 2022 - frontiersin.org
The current scientific community is facing a daunting challenge to unravel reliable natural
compounds with realistic potential to treat neurological disorders such as Alzheimer's …

Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review

Y Jiang, H Gao, G Turdu - Bioorganic chemistry, 2017 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting 25 million
people worldwide, and cholinergic hypothesis is considered as an important hypotheses in …