The composition of the gut microbiota throughout life, with an emphasis on early life

JM Rodríguez, K Murphy, C Stanton… - Microbial ecology in …, 2015 - Taylor & Francis
The intestinal microbiota has become a relevant aspect of human health. Microbial
colonization runs in parallel with immune system maturation and plays a role in intestinal …

[HTML][HTML] Challenges and future directions for studying effects of host genetics on the gut microbiome

S Sanna, A Kurilshikov, A van der Graaf, J Fu… - Nature …, 2022 - nature.com
The human gut microbiome is a complex ecosystem that is involved in its host's metabolism,
immunity and health. Although interindividual variations in gut microbial composition are …

Mucin glycan foraging in the human gut microbiome

LE Tailford, EH Crost, D Kavanaugh, N Juge - Frontiers in genetics, 2015 - frontiersin.org
The availability of host and dietary carbohydrates in the gastrointestinal (GI) tract plays a key
role in shaping the structure-function of the microbiota. In particular, some gut bacteria have …

The microbiome in inflammatory bowel disease: current status and the future ahead

AD Kostic, RJ Xavier, D Gevers - Gastroenterology, 2014 - Elsevier
Studies of the roles of microbial communities in the development of inflammatory bowel
disease (IBD) have reached an important milestone. A decade of genome-wide association …

Systematic review: the gut microbiome and its potential clinical application in inflammatory bowel disease

L Aldars-Garcia, M Chaparro, JP Gisbert - Microorganisms, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract. It is well established that the gut microbiome has a profound impact on …

[HTML][HTML] Gut microbiome function predicts response to anti-integrin biologic therapy in inflammatory bowel diseases

AN Ananthakrishnan, C Luo, V Yajnik, H Khalili… - Cell host & …, 2017 - cell.com
The gut microbiome plays a central role in inflammatory bowel diseases (IBDs)
pathogenesis and propagation. To determine whether the gut microbiome may predict …

Mucispirillum schaedleri antagonizes Salmonella virulence to protect mice against colitis

S Herp, S Brugiroux, D Garzetti, D Ring, LM Jochum… - Cell host & …, 2019 - cell.com
The microbiota and the gastrointestinal mucus layer play a pivotal role in protection against
non-typhoidal Salmonella enterica serovar Typhimurium (S. Tm) colitis. Here, we analyzed …

Biological functions of fucose in mammals

M Schneider, E Al-Shareffi, RS Haltiwanger - Glycobiology, 2017 - academic.oup.com
Fucose is a 6-deoxy hexose in the l-configuration found in a large variety of different
organisms. In mammals, fucose is incorporated into N-glycans, O-glycans and glycolipids by …

Interactions between intestinal microbiota and host immune response in inflammatory bowel disease

M Zhang, K Sun, Y Wu, Y Yang, P Tso… - Frontiers in …, 2017 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract. Although the etiology and pathogenesis of IBD remain unclear, both genetic …

[HTML][HTML] Metagenome-wide association studies: fine-mining the microbiome

J Wang, H Jia - Nature Reviews Microbiology, 2016 - nature.com
Metagenome-wide association studies (MWAS) have enabled the high-resolution
investigation of associations between the human microbiome and several complex …