Macrophage polarization states in the tumor microenvironment
AJ Boutilier, SF Elsawa - International journal of molecular sciences, 2021 - mdpi.com
The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages
are historically regarded as anti-tumor, while M2-polarized macrophages, commonly …
are historically regarded as anti-tumor, while M2-polarized macrophages, commonly …
Role of human macrophage polarization in inflammation during infectious diseases
C Atri, FZ Guerfali, D Laouini - International journal of molecular sciences, 2018 - mdpi.com
Experimental models have often been at the origin of immunological paradigms such as the
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
[HTML][HTML] Evaluating the polarization of tumor-associated macrophages into M1 and M2 phenotypes in human cancer tissue: technicalities and challenges in routine …
SD Jayasingam, M Citartan, TH Thang… - Frontiers in …, 2020 - frontiersin.org
Tumor-associated macrophages (TAMs) as immune cells within the tumor microenvironment
have gained much interests as basic science regarding their roles in tumor progression …
have gained much interests as basic science regarding their roles in tumor progression …
Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer
Despite objective responses to poly (ADP-ribose) polymerase (PARP) inhibition and
improvements in progression-free survival (PFS) compared to standard chemotherapy in …
improvements in progression-free survival (PFS) compared to standard chemotherapy in …
TAMeless traitors: macrophages in cancer progression and metastasis
Macrophages are conventionally classified into M1 and M2 subtypes according to their
differentiation status and functional role in the immune system. However, accumulating …
differentiation status and functional role in the immune system. However, accumulating …
Characterizing dedifferentiation of thyroid cancer by integrated analysis
Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …
cancer, has been hampered by imprecise and incomplete characterization of its …
Panning for gold:'model-X'knockoffs for high dimensional controlled variable selection
Many contemporary large-scale applications involve building interpretable models linking a
large set of potential covariates to a response in a non-linear fashion, such as when the …
large set of potential covariates to a response in a non-linear fashion, such as when the …
[HTML][HTML] CD68/macrosialin: not just a histochemical marker
DA Chistiakov, MC Killingsworth, VA Myasoedova… - Laboratory …, 2017 - Elsevier
CD68 is a heavily glycosylated glycoprotein that is highly expressed in macrophages and
other mononuclear phagocytes. Traditionally, CD68 is exploited as a valuable cytochemical …
other mononuclear phagocytes. Traditionally, CD68 is exploited as a valuable cytochemical …
Understanding the mysterious M2 macrophage through activation markers and effector mechanisms
T Rőszer - Mediators of inflammation, 2015 - Wiley Online Library
The alternatively activated or M2 macrophages are immune cells with high phenotypic
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …
Microglial M1/M2 polarization and metabolic states
R Orihuela, CA McPherson… - British journal of …, 2016 - Wiley Online Library
Microglia are critical nervous system‐specific immune cells serving as tissue‐resident
macrophages influencing brain development, maintenance of the neural environment …
macrophages influencing brain development, maintenance of the neural environment …