Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017

AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Nonadherence to statins: individualized intervention strategies outside the pill box

P Lansberg, A Lee, ZV Lee… - Vascular health and …, 2018 - Taylor & Francis
Poor adherence to statin therapy is linked to significantly increased risk of cardiovascular
events and death. Unfortunately, adherence to statins is far from optimal. This is an alarming …

Statin intolerance: a literature review and management strategies

DR Saxon, RH Eckel - Progress in cardiovascular diseases, 2016 - Elsevier
Statin intolerance is a commonly encountered clinical problem for which useful management
strategies exist. Although many patients report statin-related muscle symptoms, studies …

Local vascular gene therapy with apolipoprotein AI to promote regression of atherosclerosis

BK Wacker, N Dronadula, J Zhang… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—Gene therapy, delivered directly to the blood vessel wall, could potentially
prevent atherosclerotic lesion growth and promote atherosclerosis regression. Previously …

Control of LDL uptake in human cells by targeting the LDLR regulatory long non-coding RNA BM450697

RM Ray, AH Hansen, S Slott, M Taskova… - … Therapy-Nucleic Acids, 2019 - cell.com
Hypercholesterolemia is a condition that is characterized by very high levels of cholesterol in
the blood and is a major correlating factor with heart disease. Indeed, high levels of the low …

Role of anti-PCSK9 antibodies in the treatment of patients with statin intolerance

J Schreml, I Gouni-Berthold - Current medicinal chemistry, 2018 - ingentaconnect.com
Statin intolerance is usually defined as the inability of a patient to tolerate statintreatment
due to muscle-related complaints. While randomised trials show that these complaints …

An evidence-based guide to cholesterol-lowering guidelines

DD Waters, SM Boekholdt - Canadian Journal of Cardiology, 2017 - Elsevier
Since 2014, guidelines for the management of lipid disorders to reduce cardiovascular (CV)
events have been updated in the United States, the United Kingdom, Europe, and Canada …

Limosilactobacillus fermentum TY-S11 ameliorates hypercholesterolemia via promoting cholesterol excretion and regulating gut microbiota in high-cholesterol diet-fed …

Y Deng, J Wang, R Wang, Y Wang, X Shu, P Wang… - Heliyon, 2024 - cell.com
Hypercholesterolemia is a metabolic disease characterized by elevated cholesterol level in
the blood, which is a risk factor for many diseases. Probiotic intervention may be one of the …

Current drugs and nutraceuticals for the treatment of patients with dyslipidemias

M Scognamiglio, D Costa, A Sorriento… - Current …, 2019 - ingentaconnect.com
Coronary heart disease (CHD) remains the leading cause of disability and death in
industrialized Countries. Among many conditions, which contribute to the etiology and …

PCSK9 antibody-based treatment strategies for patients with statin intolerance

E Voutyritsa, C Damaskos, P Farmaki, G Kyriakos… - in vivo, 2021 - iv.iiarjournals.org
Background: Statin intolerance refers to the inability of a patient to tolerate statin therapy,
presenting muscle aches, pains, weakness and muscle inflammation. Thus, numerous …