[HTML][HTML] Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications

R Garcia - Chemical Society Reviews, 2020 - pubs.rsc.org
Fast, high-resolution, non-destructive and quantitative characterization methods are needed
to develop materials with tailored properties at the nanoscale or to understand the …

Molecular characterization of polymer networks

SPO Danielsen, HK Beech, S Wang… - Chemical …, 2021 - ACS Publications
Polymer networks are complex systems consisting of molecular components. Whereas the
properties of the individual components are typically well understood by most chemists …

Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy

MDA Norman, SA Ferreira, GM Jowett, L Bozec… - Nature …, 2021 - nature.com
Growing interest in exploring mechanically mediated biological phenomena has resulted in
cell culture substrates and 3D matrices with variable stiffnesses becoming standard tools in …

Best practices and recommendations for accurate nanomechanical characterization of heterogeneous polymer systems with atomic force microscopy

DW Collinson, RJ Sheridan, MJ Palmeri… - Progress in Polymer …, 2021 - Elsevier
The past two decades have seen atomic force microscopy (AFM) evolve from an
experimental technique to probe simple surface topography to one that can spatially map …

Atomic force microscopy-mediated mechanobiological profiling of complex human tissues

DH Cho, S Aguayo, AX Cartagena-Rivera - Biomaterials, 2023 - Elsevier
Tissue mechanobiology is an emerging field with the overarching goal of understanding the
interplay between biophysical and biochemical responses affecting development …

Cells nanomechanics by atomic force microscopy: focus on interactions at nanoscale

G Zhou, B Zhang, G Tang, XF Yu… - Advances in Physics …, 2021 - Taylor & Francis
Nanomechanics of cytoskeleton is deeply involved in physiology and regulation of cell
behavior. Atomic Force Microscopy has been extensively used for quantitative …

Recent advances in AFM-based biological characterization and applications at multiple levels

W Liang, H Shi, X Yang, J Wang, W Yang, H Zhang… - Soft Matter, 2020 - pubs.rsc.org
Atomic force microscopy (AFM) has found a wide range of bio-applications in the past few
decades due to its ability to measure biological samples in natural environments at a high …

[HTML][HTML] The viscoelasticity of adherent cells follows a single power-law with distinct local variations within a single cell and across cell lines

JG Sanchez, FM Espinosa, R Miguez, R Garcia - Nanoscale, 2021 - pubs.rsc.org
AFM-based force–distance curves are commonly used to characterize the nanomechanical
properties of live cells. The transformation of these curves into nanomechanical properties …

Biophysical approaches for applying and measuring biological forces

W Sun, X Gao, H Lei, W Wang, Y Cao - Advanced Science, 2022 - Wiley Online Library
Over the past decades, increasing evidence has indicated that mechanical loads can
regulate the morphogenesis, proliferation, migration, and apoptosis of living cells …

Universal contact stiffness of elastic solids covered with tensed membranes and its application in indentation tests of biological materials

W Yuan, Y Ding, G Wang - Acta Biomaterialia, 2023 - Elsevier
The inherent membrane tension of biological materials could vitally affect their responses to
contact loading but is generally ignored in existing indentation analysis. In this paper, the …