Neutrophils—a key component of ischemia-reperfusion injury

ZV Schofield, TM Woodruff, R Halai, MCL Wu… - Shock, 2013 - journals.lww.com
Ischemia-reperfusion injury (IRI) is a common occurrence following myocardial infarction,
transplantation, stroke, and trauma that can lead to multiple organ failure, which remains the …

The impact of ischemia/reperfusion injury on specific and non-specific, early and late chronic events after organ transplantation

W Land, K Messmer - Transplantation Reviews, 1996 - Elsevier
S ince the early days of experimental and clinical organ transplantation, all types of
posttransplant rejection events (hyperacute, acute, subacute, and chronic) have been …

Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3 …

FP Lindberg, HD Gresham, E Schwarz… - The Journal of cell …, 1993 - rupress.org
Integrin Associated Protein (IAP) is a 50-kD membrane protein which copurifies with the
integrin alpha v beta 3 from placenta and coimmunoprecipitates with beta 3 from platelets …

CD4 (+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver.

RM Zwacka, Y Zhang, J Halldorson… - The Journal of …, 1997 - Am Soc Clin Investig
The success of orthotopic liver transplantation is dependent on multiple factors including
MHC tissue compatibility and ischemic/reperfusion injury. Ischemic/reperfusion (I/R) injury in …

The role of cytokine networks in the local liver injury following hepatic ischemia/reperfusion in the rat

LM Colletti, SL Kunkel, A Walz, MD Burdick… - Hepatology, 1996 - journals.lww.com
The liver is highly susceptible to a number of pathological insults, including
ischemia/reperfusion injury. We have previously employed an animal model of hepatic …

Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and KC

AB Lentsch, H Yoshidome, WG Cheadle, FN Miller… - Hepatology, 1998 - journals.lww.com
Hepatic injury induced by ischemia and reperfusion is an important clinical problem after
liver resection or transplantation. Neutrophils are known to mediate the organ injury, but the …

Leukocytes contribute to hepatic ischemia/reperfusion injury via intercellular adhesion molecule-1-mediated venular adherence

B Vollmar, J Glasz, MD Menger, K Messmer - Surgery, 1995 - Elsevier
BACKGROUND.: Leukocytes are suggested to modulate ischemia/reperfusion injury via
membrane receptor-controlled interaction with the microvascular endothelium. METHODS …

Science review: Cell membrane expression (connectivity) regulates neutrophil delivery, function and clearance

AJE Seely, JL Pascual, NV Christou - Critical Care, 2003 - Springer
As the principal cellular component of the inflammatory host defense and contributor to host
injury after severe physiologic insult, the neutrophil is inherently coupled to patient outcome …

[HTML][HTML] Two waves of neutrophil emigration in response to corneal epithelial abrasion: distinct adhesion molecule requirements

Z Li, AR Burns, CW Smith - Investigative ophthalmology & visual …, 2006 - arvojournals.org
purpose. Corneal abrasion results in an inflammatory response characterized by leukocyte
emigration into the corneal stroma. Adhesion molecules play a critical role in leukocyte …

Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and Kupffer cells

AB Lentsch, H Yoshidome, WG Cheadle, FN Miller… - Hepatology, 1998 - journals.lww.com
Hepatic injury induced by ischemia and reperfusion is an important clinical problem after
liver resection or transplantation. Neutrophils are known to mediate the organ injury, but the …