In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Early brain development, from the embryonic period to infancy, is characterized by rapid
structural and functional changes. These changes can be studied using structural and …

Despite the great advances that the tissue engineering field has experienced over the last
two decades, the amount of in vitro engineered tissues that have reached a stage of clinical …

Current cerebral organoid technology provides excellent in vitro models mimicking the
structure and function of the developing human brain, which enables studies on normal and …

The severe imbalance between supply and demand has remained a life-threatening
situation for patients undergoing organ resection or severe tissue damage. To resolve this …

Tumors can escape immunity through multiple mechanisms, one of which is by enforcing a
state of unresponsiveness of the tumor vasculature to inflammatory cytokines. This results in …

Angiogenesis is a multistep process that requires intricate changes in cell shape to generate
new blood vessels. IF are a large family of proteins that play an important structural and …

Nutrient supply via a functional vasculature is essential during regenerative processes,
tissue growth, and homeostasis. 3D bioprinting offers the opportunity to engineer …

The pulp is a highly vascularized tissue situated in an inextensible environment surrounded
by rigid dentin walls, with the apical foramina being the only access. The pulp vascular …