Objective Intermittent fasting (IF) is a term used to describe a variety of eating patterns in
which no or few calories are consumed for time periods that can range from 12 hours to …

Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Aging is characterized generally by progressive and overall physiological decline of
functions and is observed in all animals. A long line of evidence has established the …

Most nations of the world are undergoing rapid and dramatic population ageing, which
presents great socio‐economic challenges, as well as opportunities, for individuals, families …

Alzheimer's disease (AD) is one of the fastest growing cognitive decline-related neurological
diseases. To date, effective curative strategies have remained elusive. A growing body of …

Daily calorie restriction (CR) and intermittent fasting (IF) enhance longevity and cognition but
the effects and mechanisms that differentiate these two paradigms are unknown. We …

In many animal experiments scientists and local authorities define a body-weight reduction
of 20% or more as severe suffering and thereby as a potential parameter for humane …

Dietary interventions have emerged as effective environmental inducers of brain plasticity.
Among these dietary interventions, we here highlight the impact of caloric restriction (CR: a …

Fasting is deeply entrenched in evolution, yet its potential applications to today's most
common, disabling neurological diseases remain relatively unexplored. Fasting induces an …

As people age they become increasingly susceptible to chronic and extremely debilitating
brain diseases. The precise cause of the neuronal degeneration underlying these disorders …