The human genome is pervasively transcribed, producing a majority of short and long
noncoding RNAs (lncRNAs) that can influence cellular programs through a variety of …

Solid-like protein deposits found in aged and diseased human brains have revealed a
relationship between insoluble protein accumulations and the resulting deficits in neurologic …

Since its initial involvement in numerous neurodegenerative pathologies in 2006, either as a
principal actor or as a cofactor, new pathologies implicating transactive response (TAR) …

While it is well known that 98–99% of the human genome does not encode proteins, but are
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …

Trans‐activation response DNA binding protein of 43 kDa (TDP‐43) regulates a great
variety of cellular processes in the nucleus and cytosol. In addition, a defined subset of …

Aging-related diseases represent one of the leading public health challenges of our time.
While the precise cause of many aging-related diseases remains unknown, proteins termed …

Ribonucleic acid (RNA) structures and dynamics play a crucial role in elucidating RNA
functions and facilitating the design of drugs targeting RNA and RNA-protein complexes …