Distinct regions harboring cancer stem cells (CSCs) have been identified within the
microenvironment of various tumors, and as in the case of their healthy counterparts, these …

Background Extracellular matrix (ECM) is a dynamic and complex environment
characterized by biophysical, mechanical and biochemical properties specific for each …

Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels
of sunlight exposure that do not burn the skin. Further metabolism of vitamin D to its major …

Satellite cells are adult myogenic stem cells that repair damaged muscle. The enduring
capacity for muscle regeneration requires efficient satellite cell expansion after injury, their …

Inhibitor of DNA binding (ID) proteins are transcriptional regulators that control the timing of
cell fate determination and differentiation in stem and progenitor cells during normal …

The vasculature is a prominent component of the subventricular zone neural stem cell niche.
Although quiescent neural stem cells physically contact blood vessels at specialized …

The development of hydrogel-based biomaterials represents a promising approach to
generating new strategies for tissue engineering and regenerative medicine. In order to …

Current biomarkers (DNA, RNA and protein) for oral cavity and oropharyngeal cancers
demonstrate biological variations between individuals, rendering them impractical for …

The majority of neural stem cells (NSCs) in the adult brain are quiescent, and this fraction
increases with aging. Although signaling pathways that promote NSC quiescence have …

Post-natal skeletal stem cells expressing PRX1 (pnPRX1+) have been identified in the
calvaria and in the axial skeleton. Here we characterize the location and functional capacity …