In this review, we provide an update on genome-wide association studies (GWAS) in
inflammatory bowel disease (IBD). In addition, we summarize progress in defining the …

Microbial cells significantly outnumber human cells in the body, and the microbial flora at
mucosal sites are shaped by environmental factors and, less intuitively, act on host immune …

Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Abstract We analyzed 1,900 Turkish Behçet's disease cases and 1,779 controls genotyped
with the Immunochip. The most significantly associated SNP was rs1050502, a tag SNP for …

Primary sclerosing cholangitis (PSC) is an immune-related cholangiopathy characterized by
biliary inflammation, cholestasis, and multifocal bile duct strictures. It is associated with high …

A growing body of evidence suggested that gut microbiota is associated with liver diseases
through the gut–liver axis. The imbalance of gut microbiota could be correlated with the …

Background Alkaline phosphatase (ALP) is an important serum marker in primary sclerosing
cholangitis (PSC). Patients with obstruction of the large bile ducts due to dominant strictures …

The aim of this study was to determine the antibiotic susceptibility profiles of bacteria in bile
samples and to analyze the clinical relevance of the findings as only limited information …

Background & Aims Fucosyltransferase 2 (Fut2)-mediated intestinal α1-2-fucosylation is
important for host–microbe interactions and has been associated with several diseases, but …

The etiopathogenesis of primary sclerosing cholangitis is unknown. Genetic variants of
fucosyltransferase 2 (FUT2) have been identified in genome‐wide association studies as …