It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …

Aging is a complex process indicated by low energy levels, declined physiological activity,
stress induced loss of homeostasis leading to the risk of diseases and mortality. Recent …

Parkinson's disease (PD) is a prevailing neurodegenerative disorder. Baicalein has
neuroprotective effects on PD animals, but its mechanism is not clarified. We explored …

Neurodegenerative disorders affect fifteen percent of the world's population and pose a
significant financial burden to all nations. Cognitive impairment is the seventh leading cause …

Given that the increase in the aging population has grown into one of the largest public
health issues, inflammation and oxidative stress, which are closely associated with the aging …

Methods and results: Novel work with biological clock genes that oversee circadian rhythm
may meet this critical need by focusing upon the pathways of the mechanistic target of …

Increased oxidative stress is a crucial factor for the progression of cellular senescence and
aging. The present study aimed to investigate the effects of licochalcone D (Lico D) on …

Caloric restriction promotes longevity in multiple animal models. Compounds modulating
nutrient-sensing pathways have been suggested to reproduce part of the beneficial effect of …

Background Both ambient ozone exposure and residential greenness are linked to the
aging process. However, their interactive effect on molecular biomarkers of aging (telomere …

Telomeres (TLs) reside at the end of chromosomes and are complexes of deoxyribonucleic
acid (DNA). TLs oversee cell replication and the lifespan of a cell, are involved in multiple …