Interoception refers to the representation of the internal states of an organism, and includes
the processes by which it senses, interprets, integrates, and regulates signals from within …

We review recent work on the functions of interoceptive processing, by which the nervous
system anticipates, senses, and integrates signals originating from the body. We focus on …

Obesity represents the single most important risk factor for early disability and death in
developed societies, and the incidence of obesity remains at staggering levels. CNS …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Insulin acts on the CNS to modulate behaviour and systemic metabolism. Disturbances in
brain insulin action represent a possible link between metabolic and cognitive health …

The hippocampus has previously been implicated in both cognitive and endocrine
functions,,,,,,,,,,,,,–. We simultaneously measured electrophysiological activity from the …

Examination of cognition has historically been approached from language and introspection.
However, human language–dependent definitions ignore the evolutionary roots of brain …

The vagus nerve is the primary means of neural communication between the gastrointestinal
(GI) tract and the brain. Vagally mediated GI signals activate the hippocampus (HPC), a …

Glucagon-like peptide-1 (GLP-1) is currently one of the most promising biological systems
for the development of effective obesity pharmacotherapies. Long-acting GLP-1 analogs …

Only recently have more specific circuit-probing techniques become available to inform
previous reports implicating the rodent hippocampus in orexigenic appetitive processing …