Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party
GJ Schuurhuis, M Heuser, S Freeman… - Blood, The Journal …, 2018 - ashpublications.org
Measurable residual disease (MRD; previously termed minimal residual disease) is an
independent, postdiagnosis, prognostic indicator in acute myeloid leukemia (AML) that is …
independent, postdiagnosis, prognostic indicator in acute myeloid leukemia (AML) that is …
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease
JJM Van Dongen, EA Macintyre, JA Gabert… - Leukemia, 1999 - nature.com
Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia
patients have shown that large-scale MRD studies are feasible and that clinically relevant …
patients have shown that large-scale MRD studies are feasible and that clinically relevant …
High prognostic impact of flow cytometric minimal residual disease detection in acute myeloid leukemia: data from the HOVON/SAKK AML 42A study
M Terwijn, WLJ van Putten, A Kelder… - Journal of clinical …, 2013 - ascopubs.org
Purpose Half the patients with acute myeloid leukemia (AML) who achieve complete
remission (CR), ultimately relapse. Residual treatment-surviving leukemia is considered …
remission (CR), ultimately relapse. Residual treatment-surviving leukemia is considered …
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time'quantitative reverse-transcriptase polymerase …
E Beillard, N Pallisgaard, VHJ Van der Velden, W Bi… - Leukemia, 2003 - nature.com
Real-time quantitative RT-PCR (RQ-PCR) is a sensitive tool to monitor minimal residual
disease (MRD) in leukemic patients through the amplification of a fusion gene (FG) …
disease (MRD) in leukemic patients through the amplification of a fusion gene (FG) …
Evaluating measurable residual disease in acute myeloid leukemia
F Ravandi, RB Walter, SD Freeman - Blood advances, 2018 - ashpublications.org
Mounting evidence indicates that the presence of measurable (“minimal”) residual disease
(MRD), defined as posttherapy persistence of leukemic cells at levels below morphologic …
(MRD), defined as posttherapy persistence of leukemic cells at levels below morphologic …
Impact of pretransplantation minimal residual disease, as detected by multiparametric flow cytometry, on outcome of myeloablative hematopoietic cell transplantation …
Purpose Allogeneic hematopoietic cell transplantation (HCT) benefits many patients with
acute myeloid leukemia (AML) in first remission. Hitherto, little attention has been given to …
acute myeloid leukemia (AML) in first remission. Hitherto, little attention has been given to …
Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects
VHJ Van der Velden, A Hochhaus, G Cazzaniga… - Leukemia, 2003 - nature.com
Detection of minimal residual disease (MRD) has prognostic value in many hematologic
malignancies, including acute lymphoblastic leukemia, acute myeloid leukemia, chronic …
malignancies, including acute lymphoblastic leukemia, acute myeloid leukemia, chronic …
Bioinspired multivalent DNA network for capture and release of cells
Capture and isolation of flowing cells and particulates from body fluids has enormous
implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules …
implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules …
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation
B Paiva, MB Vidriales, J Cerveró… - Blood, The Journal …, 2008 - ashpublications.org
Minimal residual disease (MRD) assessment is standard in many hematologic malignancies
but is considered investigational in multiple myeloma (MM). We report a prospective …
but is considered investigational in multiple myeloma (MM). We report a prospective …
Residual disease detected by multidimensional flow cytometry signifies high relapse risk in patients with de novo acute myeloid leukemia: a report from Children's …
Early response to induction chemotherapy is a predictor of outcome in acute myeloid
leukemia (AML). We determined the prevalence and significance of postinduction residual …
leukemia (AML). We determined the prevalence and significance of postinduction residual …