Single nucleotide polymorphisms (SNPs) are the most frequently occurring genetic variation
in the human genome, with the total number of SNPs reported in public SNP databases …

Osteoarthritis (OA) is the most prevalent form of arthritis in the elderly. A large body of
evidence, including familial aggregation and classic twin studies, indicates that primary OA …

Objective Despite many research efforts in recent decades, the major pathogenetic
mechanisms of osteoarthritis (OA), including gene alterations occurring during OA cartilage …

Background: Myocardial mass is a key determinant of cardiac muscle function and
hypertrophy. Myocardial depolarization leading to cardiac muscle contraction is reflected by …

Objective To characterize the molecular response of adult human articular cartilage to acute
mechanical injury. Methods An established ex vivo model was used to compare gene …

This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …

Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction,
and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome …

Osteoarthritis (OA) is a common disease that has a definite genetic component. Only a few
OA susceptibility genes that have definite functional evidence and replication of association …

Osteoarthritis (OA), the most prevalent form of arthritis in the elderly, is characterized by the
degradation of articular cartilage and has a strong genetic component. Our aim was to …

Osteoarthritis is a degenerative articular disease with complex pathogeny because diverse
factors interact causing a process of deterioration of the cartilage. Despite the multifactorial …