Disorder of sex development (DSD) is the term ascribed to a wide group of disorders
presenting with congenital discord between chromosomal sex and phenotypic …

The 46, XX testicular disorder of sex development (46, XX testicular DSD) is a rare
phenotype associated with disorder of the sex chromosomes. We describe the clinical …

In the female gonad, distinct signalling pathways activate ovarian differentiation while
repressing the formation of testes. Human disorders of sex development (DSDs), such as 46 …

Background: A subtype of disorders of sex development (DSD) in individuals with a 46, XX
karyotype who are phenotypically male is classified as testicular DSD (46, XX TDSD). These …

Background The translocation of SRY onto one of the two X chromosomes results in a 46,
XX testicular disorder of sex development; this is supposedly because of non‐allelic …

Sex development is a process under genetic control directing both the bi-potential gonads to
become either a testis or an ovary, and the consequent differentiation of internal ducts and …

Testicular XX disorder of sex development (XX DSD, SRY-negative), causing sterility, is
quite frequently diagnosed in pig populations, however, its molecular background is still …

Background: Very few reports are available on human XX ovotesticular disorder of sex
development involving SOX3 gene duplication. Here we aim to present a rare case of SOX3 …

Prenatal-onset androgen excess leads to abnormal sexual development in 46, XX
individuals. This androgen excess can be caused endogenously by the adrenals or gonads …

A multidisciplinary DSD clinic offers the opportunity for different specialties to learn from
each other, as each provides their own perspective and expertise to the management of …