Recent advances in the understanding of the health benefits and molecular mechanisms associated with green tea polyphenols

L Xing, H Zhang, R Qi, R Tsao… - Journal of agricultural and …, 2019 - ACS Publications
Tea, leaf, or bud from the plant Camellia sinensis, make up some of the beverages popularly
consumed in different parts of the world as green tea, oolong tea, or black tea. More …

[HTML][HTML] Sarcopenia: etiology, nutritional approaches, and miRNAs

R Cannataro, L Carbone, JL Petro, E Cione… - International journal of …, 2021 - mdpi.com
Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically
affects the quality of life. Although there is a consensus that sarcopenia is a multifactorial …

Natural dietary supplementation of anthocyanins via PI3K/Akt/Nrf2/HO-1 pathways mitigate oxidative stress, neurodegeneration, and memory impairment in a mouse …

T Ali, T Kim, SU Rehman, MS Khan, FU Amin… - Molecular …, 2018 - Springer
Well-established studies have shown an elevated level of reactive oxygen species (ROS)
that induces oxidative stress in the Alzheimer's disease (AD) patient's brain and an animal …

[HTML][HTML] Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus

MF McCarty, JJ DiNicolantonio - Progress in cardiovascular …, 2020 - ncbi.nlm.nih.gov
In light of worldwide concern regarding the recent outbreak of a deadly novel strain of
coronavirus in China, it is fortuitous that two recent discoveries point the way to effective …

[HTML][HTML] The PI3K/Akt signaling axis in Alzheimer's disease: a valuable target to stimulate or suppress?

E Razani, A Pourbagheri-Sigaroodi… - Cell Stress and …, 2021 - Elsevier
Among the long list of age-related complications, Alzheimer's disease (AD) has the most
dreadful impact on the quality of life due to its devastating effects on memory and cognitive …

[HTML][HTML] Silymarin as a natural antioxidant: an overview of the current evidence and perspectives

PF Surai - Antioxidants, 2015 - mdpi.com
Silymarin (SM), an extract from the Silybum marianum (milk thistle) plant containing various
flavonolignans (with silybin being the major one), has received a tremendous amount of …

[HTML][HTML] The multifaceted role of glutathione S-transferases in health and disease

AMA Mazari, L Zhang, ZW Ye, J Zhang, KD Tew… - Biomolecules, 2023 - mdpi.com
In humans, the cytosolic glutathione S-transferase (GST) family of proteins is encoded by 16
genes presented in seven different classes. GSTs exhibit remarkable structural similarity …

Formation and biological targets of quinones: cytotoxic versus cytoprotective effects

JL Bolton, T Dunlap - Chemical research in toxicology, 2017 - ACS Publications
Quinones represent a class of toxicological intermediates, which can create a variety of
hazardous effects in vivo including, acute cytotoxicity, immunotoxicity, and carcinogenesis …

Glutathione homeostasis and functions: potential targets for medical interventions

VI Lushchak - Journal of amino acids, 2012 - Wiley Online Library
Glutathione (GSH) is a tripeptide, which has many biological roles including protection
against reactive oxygen and nitrogen species. The primary goal of this paper is to …

Anti‐ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery

CY Shen, JG Jiang, L Yang… - British Journal of …, 2017 - Wiley Online Library
Ageing, an unanswered question in the medical field, is a multifactorial process that results
in a progressive functional decline in cells, tissues and organisms. Although it is impossible …