A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence

D Balasubramanian, L Schneper, H Kumari… - Nucleic acids …, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

A network of networks: quorum-sensing gene regulation in Pseudomonas aeruginosa

M Schuster, EP Greenberg - International journal of medical microbiology, 2006 - Elsevier
The opportunistic pathogen Pseudomonas aeruginosa possesses two N-acyl-homoserine
lactone quorum-sensing systems that regulate large, overlapping sets of genes. Recent …

The second messenger bis‐(3′‐5′)‐cyclic‐GMP and its PilZ domain‐containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa

M Merighi, VT Lee, M Hyodo… - Molecular …, 2007 - Wiley Online Library
The ubiquitous bacterial second messenger c‐di‐GMP regulates the expression of various
virulence determinants in a wide range of bacterial pathogens. Several studies have …

An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants

KH Choi, HP Schweizer - BMC microbiology, 2005 - Springer
Background Traditional gene replacement procedures are still time-consuming. They
usually necessitate cloning of the gene to be mutated, insertional inactivation of the gene …

Elucidation of Sigma Factor-Associated Networks in Pseudomonas aeruginosa Reveals a Modular Architecture with Limited and Function-Specific Crosstalk

S Schulz, D Eckweiler, A Bielecka, T Nicolai… - PLoS …, 2015 - journals.plos.org
Sigma factors are essential global regulators of transcription initiation in bacteria which
confer promoter recognition specificity to the RNA polymerase core enzyme. They provide …

Environmental predators as models for bacterial pathogenesis

H Hilbi, SS Weber, C Ragaz, Y Nyfeler… - Environmental …, 2007 - Wiley Online Library
Environmental bacteria are constantly threatened by bacterivorous predators such as free‐
living protozoa and nematodes. In the course of their coevolution with environmental …

Microarray analysis of Pseudomonas aeruginosa reveals induction of pyocin genes in response to hydrogen peroxide

W Chang, DA Small, F Toghrol, WE Bentley - BMC genomics, 2005 - Springer
Background Pseudomonas aeruginosa, a pathogen infecting those with cystic fibrosis,
encounters toxicity from phagocyte-derived reactive oxidants including hydrogen peroxide …

Cooperative pathogenicity in cystic fibrosis: Stenotrophomonas maltophilia modulates Pseudomonas aeruginosa virulence in mixed biofilm

A Pompilio, V Crocetta, S De Nicola… - Frontiers in …, 2015 - frontiersin.org
The present study was undertaken in order to understand more about the interaction
occurring between S. maltophilia and P. aeruginosa, which are frequently co-isolated from …

Comparison of virulence factors in Pseudomonas aeruginosa strains isolated from contact lens-and non-contact lens-related keratitis

MH Choy, F Stapleton… - Journal of medical …, 2008 - microbiologyresearch.org
Pseudomonas aeruginosa is one of the common pathogens associated with corneal
infection, particularly in contact lens-related keratitis events. The pathogenesis of P …

Dictyostelium as host model for pathogenesis

M Steinert, K Heuner - Cellular microbiology, 2005 - Wiley Online Library
The haploid social soil amoeba Dictyostelium discoideum has been established as a host
model for several pathogens including Pseudomonas aeruginosa, Cryptococcus …