A review on pharmacological activities and synergistic effect of quercetin with small molecule agents

H Zou, H Ye, R Kamaraj, T Zhang, J Zhang, P Pavek - Phytomedicine, 2021 - Elsevier
Background Quercetin is a natural flavonoid, which widely exists in nature, such as tea,
coffee, apples, and onions. Numerous studies have showed that quercetin has multiple …

Pharmacological activity of quercetin: an updated review

G Wang, Y Wang, L Yao, W Gu, S Zhao… - Evidence‐Based …, 2022 - Wiley Online Library
Quercetin, a natural flavonoid compound with a widespread occurrence throughout the plant
kingdom, exhibits a variety of pharmacological activities. Because of the wide spectrum of …

Dietary phytochemicals as modulators of human pregnane X receptor

J Zhang, P Pavek, R Kamaraj, L Ren… - CritiCal reviews in Food …, 2023 - Taylor & Francis
As a promiscuous xenobiotic sensor, pregnane X receptor (PXR) plays a crucial role in drug
metabolism. Since dietary phytochemicals exhibit the potential to modulate human PXR, this …

Toxicity of zearalenone and its nutritional intervention by natural products

S Jing, C Liu, J Zheng, Z Dong, N Guo - Food & Function, 2022 - pubs.rsc.org
Zearalenone (ZEN) is a toxic secondary metabolite mainly produced by fungi of the genus
Fusarium, and is often present in various food and feed ingredients such as corn and wheat …

Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment

P Xue, G Zhang, J Zhang, L Ren - Phytomedicine, 2022 - Elsevier
Background Ellagic acid (EA) is a polyphenol compound abundant in berries, walnuts,
pecans, pomegranate, cranberries, and other plant foods and exerts a wide array of …

Evolutionary research trend of Polygonatum species: a comprehensive account of their transformation from traditional medicines to functional foods

XL Li, RH Ma, F Zhang, ZJ Ni, K Thakur… - Critical Reviews in …, 2023 - Taylor & Francis
With the advances in Polygonatum research, there is a huge interest in harnessing the
valuable functional ingredients of this genus with the potential for functional foods. This …

E Se tea extract ameliorates CCl4 induced liver fibrosis via regulating Nrf2/NF-κB/TGF-β1/Smad pathway

Z Wang, P Sun, T Zhao, J Cao, Y Liu, A Khan, W Zhou… - Phytomedicine, 2023 - Elsevier
Background Liver fibrosis is a crucial progress to deteriorate liver disease. E Se tea (ES) is
an ethnic herbal tea in China that has various biological activities for human beings …

Nuclear Receptors-Mediated Endocrine Disrupting Effects of Non-Phthalate Plasticizers: A Review

J Yu, H Zou, T Zhang, J Zhang - Journal of Agricultural and Food …, 2023 - ACS Publications
In 2021, the global market for non-phthalate plasticizers reached $3.1 billion, and it is
projected to grow by 25.8% by 2025. These plasticizers have gained substantial attention as …

Environmental endocrine disruptors and pregnane X receptor action: A review

Y Liang, Y Gong, Q Jiang, Y Yu, J Zhang - Food and Chemical Toxicology, 2023 - Elsevier
The pregnane X receptor (PXR) is a kind of orphan nuclear receptor activated by a series of
ligands. Environmental endocrine disruptors (EEDs) are a wide class of molecules present …

A review of saponin intervention in metabolic syndrome suggests further study on intestinal microbiota

Z Luo, W Xu, Y Zhang, L Di, J Shan - Pharmacological research, 2020 - Elsevier
Metabolic syndrome (MetS) is a series of symptoms including insulin resistance, obesity,
dyslipidemia, elevated fasting blood glucose levels, and hepatic steatosis. As a key criterion …