Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup

A Zarbock, MK Nadim, P Pickkers, H Gomez… - Nature Reviews …, 2023 - nature.com
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

Endothelial responses in sepsis

J Joffre, J Hellman, C Ince… - American journal of …, 2020 - atsjournals.org
Endothelial cells (ECs) are vascular, nonconventional immune cells that play a major role in
the systemic response after bacterial infection to limit its dissemination. Triggered by …

The glycocalyx: a novel diagnostic and therapeutic target in sepsis

R Uchimido, EP Schmidt, NI Shapiro - Critical care, 2019 - Springer
The glycocalyx is a gel-like layer covering the luminal surface of vascular endothelial cells. It
is comprised of membrane-attached proteoglycans, glycosaminoglycan chains …

2023 update on sepsis and septic shock in adult patients: management in the emergency department

M Guarino, B Perna, AE Cesaro, M Maritati… - Journal of clinical …, 2023 - mdpi.com
Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …

Principles of fluid management and stewardship in septic shock: it is time to consider the four D's and the four phases of fluid therapy

MLNG Malbrain, N Van Regenmortel, B Saugel… - Annals of intensive …, 2018 - Springer
In patients with septic shock, the administration of fluids during initial hemodynamic
resuscitation remains a major therapeutic challenge. We are faced with many open …

[HTML][HTML] The blood-brain barrier in systemic inflammation

A Varatharaj, I Galea - Brain, behavior, and immunity, 2017 - Elsevier
The blood-brain barrier (BBB) plays a key role in maintaining the specialized
microenvironment of the central nervous system (CNS), and enabling communication with …

Human serum albumin homeostasis: a new look at the roles of synthesis, catabolism, renal and gastrointestinal excretion, and the clinical value of serum albumin …

DG Levitt, MD Levitt - International journal of general medicine, 2016 - Taylor & Francis
Serum albumin concentration (CP) is a remarkably strong prognostic indicator of morbidity
and mortality in both sick and seemingly healthy subjects. Surprisingly, the specifics of the …

Cristaloides y coloides en la reanimación del paciente crítico

J Garnacho-Montero, E Fernández-Mondéjar… - Medicina intensiva, 2015 - Elsevier
La reanimación con fluidos es esencial para la supervivencia del paciente crítico en shock,
independientemente de la causa que lo origine. Hoy en día disponemos de diversos …

Resuscitation fluids

JA Myburgh, MG Mythen - New England Journal of Medicine, 2013 - Mass Medical Soc
Resuscitation Fluids | New England Journal of Medicine Skip to main content Access provided
byTE WHATU ORA HEALTH NEW ZEALAND COUNTIES MANUKAU The New England …

Lung injury after one-lung ventilation: a review of the pathophysiologic mechanisms affecting the ventilated and the collapsed lung

J Lohser, P Slinger - Anesthesia & Analgesia, 2015 - journals.lww.com
Lung injury is the leading cause of death after thoracic surgery. Initially recognized after
pneumonectomy, it has since been described after any period of 1-lung ventilation (OLV) …