Simple Summary The formation of new blood vessels from already existing ones is a
process of high clinical relevance, since it is of great importance for both physiological and …

The last years have witnessed remarkable advances in our understanding of the emergence
and consequences of topological constraints in biological and soft matter. Examples are …

Angiogenesis, the recruitment of new blood vessels, is a critical process for the growth,
expansion, and metastatic dissemination of developing tumors. Three types of cells make up …

Biophysical cues influence many aspects of cell behavior. Stiffness of the extracellular matrix
is probed by cells and transduced into biochemical signals through mechanotransduction …

One biofabrication process that has gained tremendous momentum in the field of tissue
engineering and regenerative medicine is cell-printing or most commonly bioprinting. We …

Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-beta
(TGFβ) superfamily of cytokines. While some ligand members are potent inducers of …

The dynamics of tumor growth and associated events cover multiple time and spatial scales,
generally including extracellular, cellular and intracellular modifications. The main goal of …

Prostate cancer can be lethal in advanced stages, for which chemotherapy may become the
only viable therapeutic option. While there is no clear clinical management strategy fitting all …

Cancerous tumours have the ability to recruit new blood vessels through a process called
angiogenesis. By stimulating vascular growth, tumours get connected to the circulatory …

Favouring or thwarting the development of a vascular network is essential in fields as
diverse as oncology, cardiovascular disease or tissue engineering. As a result …