Empowering radiotherapy: Harnessing nanomedicines to enhance radiation response and boost antitumor efficacy

X Zhuo, R Aishajiang, Y Liang, P Du, P Lei, D Yu… - Coordination Chemistry …, 2024 - Elsevier
Radiotherapy (RT) is a conventional form of tumor treatment that uses X-ray irradiation to
eliminate tumors. Although RT plays an important role in treating tumor patients and …

Clinically approved carbon nanoparticles for enhanced photothermal-immunotherapy toward cancer metastasis

M Zhao, Z Li, C Yu, Q Sun, K Wang, Z Xie - Chemical Engineering Journal, 2024 - Elsevier
The development of new biomedical applications of approved drugs has several
advantages in drug translation. In this study, carbon nanoparticle suspension injection …

Harnessing Ag2S quantum dots with immune adjuvant for NIR-II fluorescence imaging-guided sonodynamic immunotherapy of colon cancer

Y Zhang, Y Zhang, Y Li, Y Fu, Y Zhao, W Zhao… - Chemical Engineering …, 2023 - Elsevier
The combination of sonodynamic therapy (SDT) with immunotherapy can not only overcome
the limitations of immunotherapy such as poor responsiveness and high side effects but also …

[HTML][HTML] Nanomaterials augmented bioeffects of ultrasound in cancer immunotherapy

X Xie, J Zhang, Y Wang, W Shi, R Tang, Q Tang… - Materials Today Bio, 2023 - Elsevier
Immunotherapy as a milestone in cancer treatment has made great strides in the past
decade, but it is still limited by low immune response rates and immune-related adverse …

Ti3C2Tx MXene quantum dots coated hollow manganese dioxide nanoparticles for tumor combination therapy and magnetic resonance imaging

L Li, Z Xing, T Liao, J Wang, Z Xu, Y Kuang… - Materials Today Chemistry, 2024 - Elsevier
Chemodynamic therapy (CDT) is a new cancer treatment that uses low-valence transition
metal ions to catalyze intracellular Fenton/Fenton-like reactions, producing hydroxyl radicals …

Simultaneous polymerization constructing Hydrogel-Elastomer composites with ultra-tough interface for robust epidermal mechanoreceptor

Z Wang, D Wang, X Li, F Yang, D Liu, F Chen - Chemical Engineering …, 2023 - Elsevier
Seamlessly integrating responsive hydrogel with antagonistic elastomer is paramount and
desired for developing multi-layered architectures with high complexity, which shows …

Small‐Bandgap Transducers Induced Carrier Separation for In Situ Dual‐Amplified Tumor Oxidative Stress

G Hu, J Wang, L Chen, H Zheng, Y Lan… - Advanced Functional …, 2024 - Wiley Online Library
The inherent and unique charge‐carrier release characteristics of piezoelectric
sonosensitizers with desired bandgap can be leveraged to initiate reactive oxygen species …

A piezoelectric catalytic cascade nanoreactor which reshapes the tumor microenvironment and promotes effective multi-dimensional therapy

Y Zheng, Y Du, GR Williams, Y Zhu, T Wang, Y Zhang… - Nano Energy, 2024 - Elsevier
The nature of the tumor microenvironment (TME) is often a hindrance to effective cancer
therapy and results in treatment failure. Here, a nanoparticle cascade catalyst has been …

Sono-blasting Triggered Cascading-Amplification of Oxidative Stress for Enhanced Interventional Therapy of Hepatocellular Carcinoma

D Li, K Zhang, K Wang, R Peng, X Liu, Y Miao… - Nano Letters, 2024 - ACS Publications
Interventional therapy is widely regarded as a highly promising treatment approach for
nonsurgical liver cancer. However, the development of drug resistance and tolerance to …

Activatable biomimetic raspberry-like nanoplatform enabled robust cascade therapy via spatiotemporal regulation of tumor immunogenicity and immunosuppression

N Li, X Wei, H Huang, J Guo, Q Li, H Yang… - Chemical Engineering …, 2024 - Elsevier
Smart nanomedicine capable of stimulating the immunity cycle and synchronously
modulating the tumor immunosuppressive microenvironment is highly desirable for …