The changing incidence of thyroid cancer

CM Kitahara, JA Sosa - Nature Reviews Endocrinology, 2016 - nature.com
During the past few decades, the incidence of thyroid cancer has increased substantially in
many countries, including the USA. The rise in incidence seems to be attributable both to the …

Molecular pathogenesis and mechanisms of thyroid cancer

M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis

Y Fu, AW Jung, RV Torne, S Gonzalez, H Vöhringer… - Nature cancer, 2020 - nature.com
We use deep transfer learning to quantify histopathological patterns across 17,355
hematoxylin and eosin-stained histopathology slide images from 28 cancer types and …

Molecular genetics and diagnosis of thyroid cancer

YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

Progress in molecular-based management of differentiated thyroid cancer

M Xing, BR Haugen, M Schlumberger - The Lancet, 2013 - thelancet.com
Substantial developments have occurred in the past 5–10 years in clinical translational
research of thyroid cancer. Diagnostic molecular markers, such as RET-PTC, RAS, and …

Redifferentiation of Iodine-Refractory BRAF V600E-Mutant Metastatic Papillary Thyroid Cancer with Dabrafenib

SM Rothenberg, DG McFadden, EL Palmer… - Clinical Cancer …, 2015 - AACR
Purpose: To determine whether the selective BRAF inhibitor, dabrafenib, can stimulate
radioiodine uptake in BRAF V600E-mutated unresectable or metastatic iodine-refractory …

Thyroid cancer epidemiology and prognostic variables

JA Sipos, EL Mazzaferri - Clinical oncology, 2010 - Elsevier
Thyroid cancer comprises a broad spectrum of diseases with variable prognoses. Although
most patients with this disease have excellent overall survival, there are some who do not …

[HTML][HTML] Anti-tumour effects of lanreotide for pancreatic and intestinal neuroendocrine tumours: the CLARINET open-label extension study

ME Caplin, M Pavel, JB Ćwikła, AT Phan… - Endocrine-related …, 2016 - erc.bioscientifica.com
In the CLARINET study, lanreotide Autogel (depot in USA) significantly prolonged
progression-free survival (PFS) in patients with metastatic pancreatic/intestinal …

The association of the BRAFV600E mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: A meta‐analysis

TH Kim, YJ Park, JA Lim, HY Ahn, EK Lee, YJ Lee… - Cancer, 2012 - Wiley Online Library
BACKGROUND: The effects of the BRAFV600E mutation on prognostic factors and poor
clinical outcomes in papillary thyroid cancer (PTC) have not been fully quantified. The …

BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …