Correlation of ThyroSeq results with surgical histopathology in cytologically indeterminate thyroid nodules

PD Chin, CY Zhu, DP Sajed, GA Fishbein, MW Yeh… - Endocrine …, 2020 - Springer
The ThyroSeq next-generation sequencing test refines the risk of malignancy in cytologically
indeterminate thyroid nodules. Specific genetic alterations have distinct cancer probabilities …

[HTML][HTML] BRAFV600E genetic testing should be recommended for Bethesda III or V thyroid nodules based on fine-needle aspiration

Y Lu, X Guo, M Yang, K Wang, G Cao, Y Liu, X Hou… - Scientific Reports, 2023 - nature.com
The preoperative diagnosis of thyroid nodules now routinely includes BRAF V600E genetic
testing in most provincial and municipal hospitals in China. This study identified the most …

Is the BRAFV600E mutation useful as a predictor of preoperative risk in papillary thyroid cancer?

JK Nam, CK Jung, BJ Song, DJ Lim, BJ Chae… - The American journal of …, 2012 - Elsevier
OBJECTIVE: Recent studies have shown that a BRAFV600E reflects poor prognosis, mainly
in Western countries. However, some clinicians in Japan have suggested that the …

[HTML][HTML] Current advances in thyroid cancer management. Are we ready for the epidemic rise of diagnoses?

D Rusinek, E Chmielik, J Krajewska, M Jarzab… - International journal of …, 2017 - mdpi.com
A rising incidence of thyroid cancers (TCs) mainly small tumors, observed during recent
years, lead to many controversies regarding treatment strategies. TCs represent a distinct …

[HTML][HTML] The evolution of biomarkers in thyroid cancer—from mass screening to a personalized biosignature

RH Grogan, EJ Mitmaker, OH Clark - Cancers, 2010 - mdpi.com
Thyroid cancer is the most common malignancy of the endocrine system. The diagnosis of
thyroid nodules, made by neck examination and ultrasonography, is a common event …

[HTML][HTML] Advances and challenges in thyroid cancer: The interplay of genetic modulators, targeted therapies, and AI-driven approaches

S Bhattacharya, RK Mahato, S Singh, GK Bhatti… - Life Sciences, 2023 - Elsevier
Thyroid cancer continues to exhibit a rising incidence globally, predominantly affecting
women. Despite stable mortality rates, the unique characteristics of thyroid carcinoma …

Thyroid cancer and lymph node metastases

OH Clark - Journal of Surgical Oncology, 2011 - Wiley Online Library
There is considerable controversy about the prognostic implications of lymph node
metastases in patients with papillary thyroid cancer and whether patients with papillary …

Improvements in Clinical Outcomes for BRAFV600E-Mutant Metastatic Colorectal Cancer

VK Morris, T Bekaii-Saab - Clinical Cancer Research, 2020 - AACR
Although the last two decades have seen a broad improvement in overall survival, colorectal
cancer is still the second leading cause of cancer deaths worldwide. Patient populations …

Both BRAF V600E Mutation and Older Age (≥65 Years) are Associated with Recurrent Papillary Thyroid Cancer

GM Howell, SE Carty, MJ Armstrong… - Annals of surgical …, 2011 - Springer
Purpose This study was designed to examine the aggressive features of BRAF-positive
papillary thyroid cancer (PTC) and association with age. Methods We compared the …

Genome-wide expression screening discloses long noncoding RNAs involved in thyroid carcinogenesis

S Liyanarachchi, W Li, P Yan… - The Journal of …, 2016 - academic.oup.com
Context: Long noncoding RNAs (lncRNAs) regulate pathological processes, yet their
potential roles in papillary thyroid carcinoma (PTC) are poorly understood. Objective: To …