[HTML][HTML] The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?
AM Di Giacomo, M Lahn, AMM Eggermont… - European Journal of …, 2023 - Elsevier
Abstract The 2022 yearly Think Tank Meeting in Siena, Tuscany (Italy), organized by the
Italian Network for Tumor Biotherapy (NIBIT) Foundation, the Parker Institute for Cancer …
Italian Network for Tumor Biotherapy (NIBIT) Foundation, the Parker Institute for Cancer …
Post-immunotherapy CTLA-4 Ig treatment improves antitumor efficacy
S Mok, D Ağaç Çobanoğlu, H Liu… - Proceedings of the …, 2024 - National Acad Sciences
Immune checkpoint therapies (ICT) improve overall survival of patients with cancer but may
cause immune-related adverse events (irAEs) such as myocarditis. Cytotoxic T lymphocyte …
cause immune-related adverse events (irAEs) such as myocarditis. Cytotoxic T lymphocyte …
Immune checkpoint inhibitors in transplantation—a case series and comprehensive review of current knowledge
J Delyon, J Zuber, R Dorent, A Poujol-Robert… - …, 2021 - journals.lww.com
Cancer is a leading cause of morbidity and deaths in solid organ transplant recipients. In
immunocompetent patients, cancer prognosis has been dramatically improved with the …
immunocompetent patients, cancer prognosis has been dramatically improved with the …
Efficacy and tolerability of tremelimumab in locally advanced or metastatic urothelial carcinoma patients who have failed first-line platinum-based chemotherapy
Purpose: Patients with advanced urothelial carcinoma who fail platinum-containing
chemotherapy (treatment fails) have a poor prognosis and limited treatment options. Recent …
chemotherapy (treatment fails) have a poor prognosis and limited treatment options. Recent …
Distinct autoantibody profiles across checkpoint inhibitor types and toxicities
H Mu-Mosley, MS von Itzstein, F Fattah, J Liu… - …, 2024 - Taylor & Francis
Immune checkpoint inhibitors (ICI) are increasingly used in combination. To understand the
effects of different ICI categories, we characterized changes in circulating autoantibodies in …
effects of different ICI categories, we characterized changes in circulating autoantibodies in …
[HTML][HTML] Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer
T Li, L Han, S Ma, W Lin, X Ba, J Yan… - Frontiers in Molecular …, 2023 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignancies worldwide and the
second leading cause of cancer-related death. In recent years, the relationship between gut …
second leading cause of cancer-related death. In recent years, the relationship between gut …
[HTML][HTML] Research advances on the immune research and prospect of immunotherapy in pituitary adenomas
D Nie, Q Fang, B Li, J Cheng, C Li, S Gui… - World Journal of …, 2021 - Springer
Background Pituitary adenomas are one type of intracranial tumor, which can be divided into
microadenoma (≤ 1 cm), macroadenoma (> 1 cm), and giant adenoma (≥ 4 cm) according …
microadenoma (≤ 1 cm), macroadenoma (> 1 cm), and giant adenoma (≥ 4 cm) according …
[HTML][HTML] Genetic heterogeneity, therapeutic hurdle confronting sorafenib and immune checkpoint inhibitors in hepatocellular carcinoma
Simple Summary Hepatocellular carcinoma (HCC) represents a worldwide health
challenge, ranking globally as the third most common cause of cancer-related mortality …
challenge, ranking globally as the third most common cause of cancer-related mortality …
[HTML][HTML] PSGL-1 is a T cell intrinsic inhibitor that regulates effector and memory differentiation and responses during viral infection
R Tinoco, EN Neubert, CJ Stairiker… - Frontiers in …, 2021 - frontiersin.org
Effective T cell differentiation during acute virus infections leads to the generation of effector
T cells that mediate viral clearance, as well as memory T cells that confer protection against …
T cells that mediate viral clearance, as well as memory T cells that confer protection against …
[HTML][HTML] The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy
P John, MC Pulanco, PM Galbo Jr, Y Wei… - Nature …, 2022 - nature.com
Immune checkpoint molecules play critical roles in regulating the anti-tumor immune
response, and tumor cells often exploit these pathways to inhibit and evade the immune …
response, and tumor cells often exploit these pathways to inhibit and evade the immune …