Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome
Bronchiolitis obliterans syndrome (BOS) is a major impediment to lung transplant survival
and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an …
and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an …
Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls
D Kruk, ACY Yeung, A Faiz, NHT Ten Hacken… - Respiratory …, 2023 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterized by irreversible
lung tissue damage. Novel regenerative strategies are urgently awaited. Cultured …
lung tissue damage. Novel regenerative strategies are urgently awaited. Cultured …
Single-cell RNA sequencing identifies hippocampal microglial dysregulation in diet-induced obesity
Obesity is a growing global concern in adults and youth with a parallel rise in associated
complications, including cognitive impairment. Obesity induces brain inflammation and …
complications, including cognitive impairment. Obesity induces brain inflammation and …
FOXF1 reverses lung fibroblasts transdifferentiation via inhibiting TGF-β/SMAD2/3 pathway in silica-induced pulmonary fibrosis
B Hu, X Zhang, H Fan, X Jin, Y Qi, R Liu, X Li… - International …, 2024 - Elsevier
Silicosis is one of the most common and severe types of pneumoconiosis and is
characterized by lung dysfunction, persistent lung inflammation, pulmonary nodule …
characterized by lung dysfunction, persistent lung inflammation, pulmonary nodule …
FOXF1 attenuates TGF‑β1‑induced bronchial epithelial cell injury by inhibiting CDH11‑mediated Wnt/β‑catenin signaling
Q Chen, X Liao, L Lin, L Wu… - Experimental and …, 2023 - spandidos-publications.com
Abstract Forkhead box F1 (FOXF1) has been reported to be associated with lung
development. However, the role of FOXF1 in asthma is still not fully understood. In the …
development. However, the role of FOXF1 in asthma is still not fully understood. In the …
Lef1 is transcriptionally activated by Klf4 and suppresses hyperoxia-induced alveolar epithelial cell injury
M Yang, X Huang, F Shen, J Yi, Y Meng… - Experimental Lung …, 2022 - Taylor & Francis
Purpose Bronchopulmonary dysplasia (BPD) is a long-term respiratory condition. More than
a quarter of extremely premature newborns are harmed by BPD. At present, there are no …
a quarter of extremely premature newborns are harmed by BPD. At present, there are no …
The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation
Y Aoki, NM Walker, K Misumi, T Mimura, R Vittal… - The Journal of Heart and …, 2023 - Elsevier
Background Small airway inflammation and fibrosis or bronchiolitis obliterans (BO) is the
predominant presentation of chronic lung allograft dysfunction (CLAD) post-lung …
predominant presentation of chronic lung allograft dysfunction (CLAD) post-lung …