A crosstalk between epigenetic modulations and non-alcoholic fatty liver disease progression
M Ramezani, M Zobeiry, S Abdolahi, B Hatami… - … -Research and Practice, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has recently emerged as a major public health
concern worldwide due to its rapidly rising prevalence and its potential to progress into end …
concern worldwide due to its rapidly rising prevalence and its potential to progress into end …
[HTML][HTML] Epigenetics in diabetic cardiomyopathy
X Ma, S Mei, Q Wuyun, L Zhou, D Sun, J Yan - Clinical Epigenetics, 2024 - Springer
Diabetic cardiomyopathy (DCM) is a critical complication that poses a significant threat to the
health of patients with diabetes. The intricate pathological mechanisms of DCM cause …
health of patients with diabetes. The intricate pathological mechanisms of DCM cause …
Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice
J Mononen, M Taipale, M Malinen… - Nucleic Acids …, 2024 - academic.oup.com
Most common genetic variants associated with disease are located in non-coding regions of
the genome. One mechanism by which they function is through altering transcription factor …
the genome. One mechanism by which they function is through altering transcription factor …
[HTML][HTML] Homotherapy for heteropathy: therapeutic effect of Butein in NLRP3-driven diseases
W Liao, Y Li, J Liu, Y Mou… - Cell …, 2024 - biosignaling.biomedcentral.com
Aberrant inflammatory responses drive the initiation and progression of various diseases,
and hyperactivation of NLRP3 inflammasome is a key pathogenetic mechanism …
and hyperactivation of NLRP3 inflammasome is a key pathogenetic mechanism …
[HTML][HTML] The suppression of HSPA8 attenuates NLRP3 ubiquitination through SKP2 to promote pyroptosis in sepsis-induced lung injury
J Liu, K Song, B Lin, Z Chen, Y Liu, X Qiu, Q He, Z Zuo… - Cell & Bioscience, 2024 - Springer
Background Acute lung injury (ALI) is strongly associated with hospitalization and mortality
in patients with sepsis. Recent evidence suggests that pyroptosis mediated by NLRP3 (NOD …
in patients with sepsis. Recent evidence suggests that pyroptosis mediated by NLRP3 (NOD …
LncRNA Gm28382 promotes lipogenesis by interacting with miR-326-3p to regulate ChREBP signaling pathway in NAFLD
S Yang, Y Zhang, Y Zhang, L Yin, X Han, X Zhao… - International …, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) have been demonstrated to play vital roles in the
pathogenesis of nonalcoholic fatty liver disease (NAFLD). However, their biological roles …
pathogenesis of nonalcoholic fatty liver disease (NAFLD). However, their biological roles …
[HTML][HTML] lincRNA00907 promotes NASH progression by targeting miRNA-942-5p/TAOK1
G Du, Z Jiang, T Xia, M Liu, Z Liu, H Zhou… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Objective: The study aims to examine the involvement of lincRNA00907 in the advancement
of non-alcoholic steatohepatitis (NASH). Methods: The examination was conducted to …
of non-alcoholic steatohepatitis (NASH). Methods: The examination was conducted to …
[HTML][HTML] CircMLH3 induces mononuclear macrophage pyroptosis in sepsis by sponging miR-590-3p to regulate TAK1 expression
Q Sun, Z Hu, W Huang, X Liu, X Wu, W Chang… - International Journal of …, 2024 - Elsevier
Sepsis is a fatal syndrome characterized by uncontrolled systemic inflammatory responses.
Circular RNAs (circRNAs) are involved in the modulation of various pathophysiological …
Circular RNAs (circRNAs) are involved in the modulation of various pathophysiological …
Inhibition of ROS/caspase-3/GSDME-mediated pyroptosis alleviates high glucose-induced injury in AML-12 cells
X Wang, S Ye, L Tong, J Gao, Y Zhang, Y Qin - Toxicology in Vitro, 2024 - Elsevier
Diabetic liver injury (DLI) is a chronic complication of the liver caused by diabetes, and its
has become one of the main causes of nonalcoholic fatty liver disease (NAFLD). The …
has become one of the main causes of nonalcoholic fatty liver disease (NAFLD). The …
[HTML][HTML] Increasing CB2 Receptor Activity after Early Life Stress Prevents Depressive Behavior in Female Rats
SL Andersen - Biomolecules, 2024 - mdpi.com
Early adversity, the loss of the inhibitory GABAergic interneuron parvalbumin, and elevated
neuroinflammation are associated with depression. Individuals with a maltreatment history …
neuroinflammation are associated with depression. Individuals with a maltreatment history …