Transfer of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) from oral exposure into cow's milk–Part I: state of …

T Krause, JL Moenning, J Lamp, R Maul… - Nutrition research …, 2022 - cambridge.org
Polychlorinated dibenzo-para-dioxins (PCDDs) and dibenzofurans (PCDFs)(collectively and
colloquially referred to as 'dioxins') as well as polychlorinated biphenyls (PCBs) are …

[HTML][HTML] Ionophore coccidiostats–disposition kinetics in laying hens and residues transfer to eggs

A Bello, J Henri, A Viel, JP Mochel, B Poźniak - Poultry Science, 2023 - Elsevier
Poultry production is linked with the use of veterinary medicinal products to manage
diseases. Ionophore coccidiostats have been permitted for use as feed additives within the …

[HTML][HTML] Pregnancy-specific physiologically-based toxicokinetic models for bisphenol A and bisphenol S

J Gingrich, D Filipovic, R Conolly, S Bhattacharya… - Environment …, 2021 - Elsevier
Predictions from physiologically based toxicokinetic (PBTK) models can help inform human
health risk assessment for potentially toxic chemicals in the environment. Bisphenol S (BPS) …

A generalized physiologically based kinetic model for fish for environmental risk assessment of pharmaceuticals

J Wang, TM Nolte, SF Owen, R Beaudouin… - Environmental …, 2022 - ACS Publications
An increasing number of pharmaceuticals found in the environment potentially impose
adverse effects on organisms such as fish. Physiologically based kinetic (PBK) models are …

[HTML][HTML] A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in broiler chickens and laying hens

L Yuan, WC Chou, ED Richards, LA Tell… - Food and Chemical …, 2022 - Elsevier
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) commonly used in food-
producing animals, including chickens in an extralabel manner. This study aimed to develop …

[HTML][HTML] An open source physiologically based kinetic model for the chicken (Gallus gallus domesticus): Calibration and validation for the prediction residues in tissues …

LS Lautz, C Nebbia, S Hoeks, R Oldenkamp… - Environment …, 2020 - Elsevier
Xenobiotics from anthropogenic and natural origin enter animal feed and human food as
regulated compounds, environmental contaminants or as part of components of the diet …

Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part I: Cattle and swine

Z Lin, M Li, YS Wang, LA Tell… - Journal of veterinary …, 2020 - Wiley Online Library
Physiologically based pharmacokinetic (PBPK) models for chemicals in food animals are a
useful tool in estimating chemical tissue residues and withdrawal intervals. Physiological …

[HTML][HTML] Generic physiologically based kinetic modelling for farm animals: Part I. Data collection of physiological parameters in swine, cattle and sheep

LS Lautz, J Dorne, R Oldenkamp, AJ Hendriks… - Toxicology letters, 2020 - Elsevier
Physiologically based kinetic (PBK) models for farm animals are of growing interest in food
and feed safety with key applications for regulated compounds including quantification of …

In silico methods for environmental risk assessment: Principles, tiered approaches, applications, and future perspectives

MC Astuto, MR Di Nicola, JV Tarazona… - In Silico methods for …, 2022 - Springer
This chapter aims to introduce the reader to the basic principles of environmental risk
assessment of chemicals and highlights the usefulness of tiered approaches within weight of …

Interspecies scaling of toxicity reference values in human health versus ecological risk assessments: A critical review

HJ Clewell, PC Fuchsman - … Environmental Assessment and …, 2024 - Wiley Online Library
Risk assessments that focus on anthropogenic chemicals in environmental media—whether
considering human health or ecological effects—often rely on toxicity data from …