Recent advances in the natural products-based lead discovery for new agrochemicals

P Zhang, CB Duan, B Jin, AS Ali, X Han, H Zhang… - Advanced …, 2023 - Elsevier
Crops will be harmed by fungi, pests and weeds during their growth. In the past half century,
scientists have conducted in-depth research on natural products extracted from …

Recent advances for alkaloids as botanical pesticides for use in organic agriculture

Y Wu, D Ren, C Gao, J Li, B Du, Z Wang… - International Journal of …, 2021 - Taylor & Francis
Alkaloids are the most basic organic compounds involved in crucial physiological activities
and are widely found in plants, animals and microorganisms. Due to the anti-inflammatory …

Design, synthesis, antibacterial activity, and mechanisms of novel 1, 3, 4-thiadiazole derivatives containing an amide moiety

Z Wu, J Shi, J Chen, D Hu, B Song - Journal of Agricultural and …, 2021 - ACS Publications
To discover novel antibacterial agents, a series of novel 1, 3, 4-thiadiazole derivatives
containing an amide moiety were designed and synthesized, and their antibacterial activities …

Quinolizidine Alkaloids with Antiviral and Insecticidal Activities from the Seeds of Sophora tonkinensis Gagnep

J Zou, L Zhao, P Yi, Q An, L He, Y Li… - Journal of Agricultural …, 2020 - ACS Publications
The discovery of novel, effective, and botanical pesticides is one of the main strategies for
modern plant protection and insect pest control. During the search for novel botanical …

Construction of cholesterol oxime ether derivatives containing isoxazoline/isoxazole fragments and their agricultural bioactive properties/control efficiency

H Xu, K Zhang, M Lv, M Hao - Journal of Agricultural and Food …, 2021 - ACS Publications
To explore natural-product-based pesticidal candidates and high value-added application of
cholesterol in agriculture, oximinoether derivatives of cholesterol-containing …

Design, synthesis and various bioactivity of acylhydrazone-containing matrine analogues

W Ni, H Song, L Wang, Y Liu, Q Wang - Molecules, 2023 - mdpi.com
Compounds with acylhydrazone fragments contain amide and imine groups that can act as
electron donors and acceptors, so they are easier to bind to biological targets and thus …

Optimization of osthole in the lactone ring as an agrochemical candidate: synthesis, characterization, and pesticidal activities of osthole amide/ester derivatives and …

J Xu, M Lv, T Li, H Wen, H Xu - Journal of Agricultural and Food …, 2023 - ACS Publications
Structural modification of natural products is one of the important ways in the discovery of
novel pesticides. Based on a diversity-oriented synthesis strategy, herein, two series of …

Optimization of osthole in the lactone ring: Structural elucidation, pesticidal activities, and control efficiency of osthole ester derivatives

S Li, M Lv, Z Sun, M Hao, H Xu - Journal of Agricultural and Food …, 2021 - ACS Publications
Here, we prepared a series of novel osthole-type ester derivatives modified in the lactone
ring of osthole, which is isolated from Cnidium monnieri. The positions of H-3 and H-4 of the …

Construction of oxime ester derivatives of osthole from Cnidium monnieri, and evaluation of their agricultural activities and control efficiency

Z Ren, M Lv, T Li, M Hao, S Li… - Pest Management …, 2020 - Wiley Online Library
BACKGROUND In order to discover natural‐product‐based pesticidal candidates, a series
of coumarin‐like derivatives containing oxime ester fragments at the C‐8 position were …

Development of botanical pesticides: Exploration on the phenotype of vestigial wings of insect pests induced by plant natural products or their derivatives by blocking …

Z Sun, M Lv, W Huang, T Li, H Xu - Journal of Agricultural and …, 2022 - ACS Publications
Unlike faster-acting conventional insecticides, some botanical insecticides exhibit growth
inhibitory activity against some insect pests. One of the distinguishing features of growth …