Background Oocyte growth is accompanied by follicular development in mammalian
ovaries. Since the discovery of two oocyte‐derived factors, growth differentiation factor 9 …

The environment that the cumulus oocyte complex (COC) is exposed to during either in vivo
or in vitro maturation (IVM) can have profound effects on the success of fertilisation and …

The role of metabolism in ovarian aging is poorly described, despite the fact that ovaries fail
earlier than most other organs. Growing interest in ovarian function is being driven by recent …

Obesity, diabetes, and related metabolic disorders are major health issues worldwide. As
the epidemic of metabolic disorders continues, the associated medical co-morbidities …

Oocyte quality is a critical factor limiting the efficiency of assisted reproductive technologies
(ART) and pregnancy success in farm animals and humans. ART success is diminished with …

This study investigated bovine conceptus-induced modifications to the endometrial
transcriptome related to effects of interferon tau (IFNT), conceptus origin (in vivo vs. in vitro) …

Aromatase is the enzyme complex that catalyses the synthesis of oestrogens from
androgens, and therefore it has unique potential to influence the physiological balance …

Growing oocytes in vitro from the most immature stages until they are developmentally
competent is a major goal of reproductive technology, requiring fundamental knowledge of …

Many couples present fertility problems at their reproductive age, and although in the last
years, the efficiency of assisted reproduction techniques has increased, these are still far …

Recent genomic studies have shed light on the impact of in vitro culture (IVC) on embryonic
homeostasis and the differential gene expression profiles associated with lower …