The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway

V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - ASPET
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

[HTML][HTML] Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies

JW Lampe - The American journal of clinical nutrition, 1999 - Elsevier
Epidemiologic data support the association between high intake of vegetables and fruits and
low risk of chronic disease. There are several biologically plausible reasons why …

A non-threshold model to estimate carcinogenic risk of nitrate-nitrite in drinking water

R Noori, F Farahani, C Jun, S Aradpour… - Journal of Cleaner …, 2022 - Elsevier
Abstract Understanding nitrate–nitrite (NO 3−− NO 2−) levels in drinking water and the
associated non-carcinogenic and carcinogenic health risks are essential to protect public …

Nitrites and nitrates from food additives and natural sources and cancer risk: results from the NutriNet-Santé cohort

E Chazelas, F Pierre, N Druesne-Pecollo… - International journal …, 2022 - academic.oup.com
Background Nitrates and nitrites occur naturally in water and soil. They are also used as
food additives (preservatives) in processed meats. They could play a role in the …

Role of plant polyphenols in genomic stability

LR Ferguson - … Research/Fundamental and Molecular Mechanisms of …, 2001 - Elsevier
Polyphenols are a large and diverse class of compounds, many of which occur naturally in a
range of food plants. The flavonoids are the largest and best-studied group of these. A range …

[HTML][HTML] Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis

AM De Marzo, VL Marchi, JI Epstein… - The American journal of …, 1999 - Elsevier
Proliferation in the setting of longstanding chronic inflammation appears to predispose to
carcinoma in the liver, large bowel, urinary bladder, and gastric mucosa. Focal prostatic …

Municipal drinking water nitrate level and cancer risk in older women: the Iowa Women's Health Study

PJ Weyer, JR Cerhan, BC Kross, GR Hallberg… - …, 2001 - journals.lww.com
Nitrate contamination of drinking water may increase cancer risk, because nitrate is
endogenously reduced to nitrite and subsequent nitrosation reactions give rise to N-nitroso …

[HTML][HTML] The role of red and processed meat in colorectal cancer development: a perspective

M Oostindjer, J Alexander, GV Amdam, G Andersen… - Meat science, 2014 - Elsevier
This paper is based on a workshop held in Oslo, Norway in November 2013, in which
experts discussed how to reach consensus on the healthiness of red and processed meat …

Cigarette smoking and the progression of multiple sclerosis

MA Hernán, SS Jick, G Logroscino, MJ Olek… - Brain, 2005 - academic.oup.com
An increased risk of multiple sclerosis among smokers has been found in several
prospective epidemiological studies. The association between smoking and progression of …

[HTML][HTML] Ingested nitrate, disinfection by-products, and risk of colon and rectal cancers in the Iowa Women's Health Study cohort

RR Jones, CT DellaValle, PJ Weyer, K Robien… - Environment …, 2019 - Elsevier
Background N-nitroso compounds (NOC) formed endogenously after nitrate/nitrite ingestion
and disinfection by-products (DBPs) are suspected colorectal carcinogens, but …