[HTML][HTML] The evolution of neurofilament light chain in multiple sclerosis

C Ferreira-Atuesta, S Reyes, G Giovanonni… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …

[HTML][HTML] Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges

Z Khan, GD Gupta, S Mehan - Journal of clinical medicine, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

[HTML][HTML] Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis

J Åkesson, S Hojjati, S Hellberg, J Raffetseder… - Nature …, 2023 - nature.com
Sensitive and reliable protein biomarkers are needed to predict disease trajectory and
personalize treatment strategies for multiple sclerosis (MS). Here, we use the highly …

[HTML][HTML] Myelitis features and outcomes in CNS demyelinating disorders: comparison between multiple sclerosis, MOGAD, and AQP4-IgG-positive NMOSD

G Fadda, EP Flanagan, L Cacciaguerra… - Frontiers in …, 2022 - frontiersin.org
Inflammatory myelopathies can manifest with a combination of motor, sensory and
autonomic dysfunction of variable severity. Depending on the underlying etiology, the …

The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

K Ruprecht - Expert review of clinical immunology, 2020 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system. While its exact etiology is unknown, it is generally believed that MS …

[HTML][HTML] The role of herpes simplex virus type 1 infection in demyelination of the central nervous system

R Bello-Morales, S Andreu… - International Journal of …, 2020 - mdpi.com
Herpes simplex type 1 (HSV-1) is a neurotropic virus that infects the peripheral and central
nervous systems. After primary infection in epithelial cells, HSV-1 spreads retrogradely to the …

[HTML][HTML] Intrathecal inflammation in progressive multiple sclerosis

S Monaco, R Nicholas, R Reynolds… - International journal of …, 2020 - mdpi.com
Progressive forms of multiple sclerosis (MS) are associated with chronic demyelination,
axonal loss, neurodegeneration, cortical and deep gray matter damage, and atrophy. These …

The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis

CS Simonsen, HØ Flemmen… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background Diagnostic criteria for multiple sclerosis have been developed to guide the
diagnostic process. In the latest revision of the McDonald criteria, the presence of …

[HTML][HTML] The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence

A Hanaford, SC Johnson - Orphanet Journal of Rare Diseases, 2022 - Springer
Background Genetic mitochondrial diseases represent a significant challenge to human
health. These diseases are extraordinarily heterogeneous in clinical presentation and …

[HTML][HTML] Identification and clinical validation of key extracellular proteins as the potential biomarkers in relapsing-remitting multiple sclerosis

M Li, H Chen, P Yin, J Song, F Jiang, Z Tang… - Frontiers in …, 2021 - frontiersin.org
Background Multiple sclerosis (MS) is a demyelinating disease of the central nervous
system (CNS) mediated by autoimmunity. No objective clinical indicators are available for …