The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2019)

S Umemura, H Arima, S Arima, K Asayama… - Hypertension …, 2019 - nature.com
The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Treatment of resistant and refractory hypertension

MC Acelajado, ZH Hughes, S Oparil… - Circulation …, 2019 - Am Heart Assoc
Resistant hypertension (RHTN) is defined as uncontrolled blood pressure despite the use
of≥ 3 antihypertensive agents of different classes, including a diuretic, usually thiazide-like …

Aldosterone synthase inhibition with lorundrostat for uncontrolled hypertension: the target-HTN randomized clinical trial

LJ Laffin, D Rodman, JM Luther, A Vaidya, MR Weir… - Jama, 2023 - jamanetwork.com
Importance Excess aldosterone production contributes to hypertension in both classical
hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …

[HTML][HTML] Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised …

B Williams, TM MacDonald, S Morant, DJ Webb… - The Lancet, 2015 - thelancet.com
Background Optimal drug treatment for patients with resistant hypertension is undefined. We
aimed to test the hypotheses that resistant hypertension is most often caused by excessive …

Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic …

B Pitt, L Kober, P Ponikowski… - European heart …, 2013 - academic.oup.com
Abstract Aims Mineralocorticoid receptor antagonists (MRAs) improve outcomes in patients
with heart failure and reduced left ventricular ejection fraction (HFrEF), but their use is limited …

Prevalence of resistant hypertension in the United States, 2003–2008

SD Persell - Hypertension, 2011 - Am Heart Assoc
The prevalence of resistant hypertension is unknown. Much previous knowledge comes
from referral populations or clinical trial participants. Using data from the National Health …

Hypertension in chronic kidney disease

SM Hamrahian, B Falkner - Hypertension: from basic research to clinical …, 2017 - Springer
Hypertension, a global public health problem, is currently the leading factor in the global
burden of disease. It is the major modifiable risk factor for heart disease, stroke and kidney …

Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the …

DA Calhoun, D Jones, S Textor, DC Goff, TP Murphy… - …, 2008 - Am Heart Assoc
Resistant hypertension is a common clinical problem faced by both primary care clinicians
and specialists. While the exact prevalence of resistant hypertension is unknown, clinical …

New approaches in the treatment of hypertension

S Oparil, RE Schmieder - Circulation research, 2015 - Am Heart Assoc
Hypertension is the most common modifiable risk factor for cardiovascular disease and
death, and lowering blood pressure with antihypertensive drugs reduces target organ …

[HTML][HTML] Hypertension in the elderly

N Lionakis, D Mendrinos, E Sanidas… - World journal of …, 2012 - ncbi.nlm.nih.gov
The elderly are the most rapidly growing population group in the world. Data collected over
a 30-year period have demonstrated the increasing prevalence of hypertension with age …