Plasma renin levels can be used to classify hypertension. A significant proportion of
hypertensive individuals display a low‐renin profile and thus low‐renin hypertension (LRH) …

The stimulation of mineralocorticoid receptors is linked to the development of hypertension
and cardiovascular or renal damage in patients with diabetes, and the blockade of these …

The nonsteroidal mineralocorticoid receptor (MR) blocker esaxerenone has demonstrated
good antihypertensive activity in a variety of patients, including those with uncomplicated …

Abstract OBJECTIVES African and African American hypertensives tend to retain salt and
water, with lower levels of plasma renin and more resistant hypertension. We tested the …

Resistant hypertension increases the risk for cardiovascular events and end-stage kidney
disease. 1 Few therapies exist for people with chronic kidney disease (CKD). In a double …

Hypertension (defined as BP> 140/90 mm Hg) is a global burden, affecting as many as 1
billion individuals worldwide and causing 7.5 million deaths (12.8% of all deaths) per year. 1 …

Background—There is continuing variation in diagnosis and estimated prevalence of
primary hyperaldosteronism. The higher estimates encourage search for adrenal adenomas …

Context: Animal studies have demonstrated that dietary sodium intake is a major influence in
the pathogenesis of aldosterone-induced effects in the heart such as left ventricular (LV) …

Renal sympathetic denervation has shown promise in treating hypertension resistant to drug
therapy. This procedure lowers blood pressure via targeted attenuation of renal sympathetic …

Background Currently there is no consensus regarding which add-on therapy to use in
resistant hypertension. This study was designed to compare two treatment options …