Abstract Background Preserved Ratio Impaired Spirometry (PRISm) is defined as
FEV1/FVC≥ 70% and FEV1< 80% pred by pulmonary function test (PFT). It has highly …

Background The mechanisms underlying airflow obstruction in COPD cannot be
distinguished by standard spirometry. We ascertain whether mathematical modeling of …

Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease. Aiming at
assessing the effect of total saponins from American ginseng on COPD, both the chemical …

Rationale and Objectives To evaluate the role of radiomics based on Chest Computed
Tomography (CT) in the identification and severity staging of chronic obstructive pulmonary …

Background The correlation between visual emphysema patterns and subsequent
progression of disease may provide a way to enrich a study population for treatment trials of …

The purpose of this study was to investigate a preclinical spectral photon-counting CT
(SPCCT) prototype compared to conventional CT for pulmonary imaging. A custom-made …

The mechanisms linking reduced diffusing capacity of the lung for carbon monoxide (Dlco)
to dyspnea and exercise intolerance across the chronic obstructive pulmonary disease …

Treatment of COPD should reflect the complexity and heterogeneity of the disease and be
tailored to individual patients. Major goals of COPD treatment are symptom reduction and …

Airway mucus obstruction is a key feature of cystic fibrosis (CF) and chronic obstructive
pulmonary disease (COPD). The thin layer of mucus that covers healthy airway surfaces has …

Background The clinical significance of visually evident emphysema on CT images in
individuals without spirometric evidence of chronic obstructive pulmonary disease (COPD) …